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Mineral deposition occurred in the basal matrix of multilayered areas as indicated by von Kossa staining, and transmission electron microscopy and electron diffraction identified the mineral as apatite. Maximum voluntary concentric torque of the hamstring and quadriceps muscles of both legs was assessed using a Norm isokinetic dynamometer at angular velocities of 12 degrees, 60 degrees, 180 degrees and 300 degrees/s. Influenced by a variety of factors, pathophysiological microvascular changes provoke anterior ischemic neuropathy with sudden painless loss of vision, irreversible in most cases.

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Lateral mobility of the antagonist-occupied V2 vasopressin receptor in membranes of renal epithelial cells. The binding of native, oxidized, proteolyzed (alpha-chymotrypsin-treated), or lipolyzed (sphingomyelinase- or phospholipase A(2)-treated) LDL particles to proteoglycans were measured in microtiter well assays at pH 5.5-7.5. We present the case of a 38-year-old male who presented a combined MCL avulsion injury and PCL tear treated surgically. A modification of the standard null hypothesis of zero difference in fit is proposed allowing for testing an interval hypothesis that the difference in fit between models is small, rather than zero.

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To investigate the effects of two different fluoride concentrations on the expression of enamel proteins, alkaline phosphatase (ALP), cytokines and interleukins by an ameloblast-derived cell line. Insulin responses to glucose: evidence for a two pool system in man. A clinical trial of troxerutin in venous insufficiency of the lower limb. In both groups, training induced significant modification in most of the cardio-respiratory parameters, ie peak oxygen uptake, peak carbon dioxide output, respiratory exchange ratio, ventilation/min to oxygen-uptake ratio and oxygen-uptake to heart-rate ratio. The results of MALDI-TOF mass spectrometry indicate that the mature form of this antibacterial peptide is 35 amino acid residues in length and has an amidated C-terminal isoleucine.

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Twenty-four hour energy expenditure increased significantly by about 750 kJ with all EGCG-caffeine mixtures compared with placebo. LncRNA PlncRNA-1 Promotes Colorectal Cancer Cell Progression by Regulating PI3K/Akt Signaling Pathway. The average time of external fixation was 8 months and the average time to union was 7.1 months. Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the Duffy blood group antigen.

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Ehlers-Danlos syndromes (EDS) are a group of inherited connective tissue disorders, characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. The present studies were undertaken to determine the hemolytic potential of propanil, and, if positive, the role of metabolites in this hemotoxicity. Improvement in air-bone gap was noted in 6 of 7 subjects with an average closure of 17 dB. typhimurium in the bile, conditions reflecting a state of oral tolerance. Xenopus oocytes are arrested in prophase of the first meiotic division.

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Ion complexation: a route to enhanced block copolymer alignment with electric fields. The committee developed a draft consisting of set of recommendations, which were then reviewed and approved by the entire Executive Committee. The LAMP products were sandwiched between the anti-FITC and the anti-BIO, and the accumulation of the Fe3O4 magnetic nanoparticles enabled the visual detection of ES.

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Maternally supplied germ plasm is essential for germ lineage establishment in many species, but the molecular details are still largely unknown, especially in vertebrates, and identification of novel factors that localize to germ plasm is desirable. We hypothesize that this promotes advanced olfactory processing associated with chemical communication, orientation and social interactions. To some extent, these associations may be attributed to the high amount of polyphenols and bioactive compounds in typical foods conforming this traditional dietary pattern.

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We examined whether systemic treatment with thioctic acid or dihydrolipoic acid is protective against direct- and indirect-acting excitotoxins. On the other hand, the dioxins TEQ concentration in paddy field was significantly high, although organic carbon content was relatively low.

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A review of national policies and strategies to improve quality of health care and patient safety: a case study from Lebanon and Jordan. The study demonstrates the feasibility of using wearable sensors to record objective outcomes in PD-related clinical trials.

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Recent studies reveal that protein arginine methylation is more common and widespread than previously thought and that it is implicated in a number of key cellular processes including signal transduction. Ultrasound-guided thrombin injection (UGTI) of femoral artery pseudoaneurysms after endovascular procedures is an effective therapy. In this study we analyzed the anthracycline-induced cardiotoxicity and the possible preventive role of dexrazoxane in children. The paper begins with an overview of how individuals with disabilities have historically been excluded from society based on limited access and minimal opportunities afforded to them.

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Identifying those variants from whole-genome or exome data can be both scientifically challenging and time consuming. Characterization of the biosynthesis (secretion and immunity) of lactococcin Z. (18)FDG-PET/CT is better than CT in judging tumor residue of HCC after treatment of TACE combined with RFA or surgery, and in guiding further treatment of HCC. The study aimed to evaluate the increasing trend in global ranking of Iranian medical universities websites emphasizing on comparative approach. Here we report a novel antibody-catalyzed intramolecular Michael addition of aldehydes and ketones to enones.

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All four of the explanted alumina liners revealed evidence of rim contact with the metal neck of the femoral component. Addition of Dexmedetomidine to QX-314 Enhances the Onset and Duration of Sciatic Nerve Block in Rats. Transient macroscopic quantum superposition states in degenerate parametric oscillation using squeezed reservoir fields.

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Approximate dislocation densities determined from ECC images compare well to those determined by CC-EBSD. Several studies have also explored mechanisms underlying the mechanisms of neuroprotection by therapeutic hypothermia. Our objective was to summarize mortality outcomes and explore disease and social factors related to mortality.

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CDC15, an essential cell cycle gene in Saccharomyces cerevisiae, encodes a protein kinase domain. Seven severely burned patients who suffered from a severe metal dust explosion injury were recruited in this study. Laparoscopic partial nephrectomy with segmental renal artery clamping: technique and clinical outcomes. The spindle, tendon organ, light and heavy pressure receptors in medial gastrocnemius muscle were identified by recording discharges of single afferent fiber in medial gastrocnemius nerve from fine filaments by dissection. The effect of methylene blue phototreatment on plasma proteins and in vitro coagulation capability of single-donor fresh-frozen plasma.

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right), rather than the effect of the manipulation on this measure (experimental vs. Choreiform movements were moderately severe and remitted several hours after discontinuation of theophylline or over days in the patient who remained on the drug. The results of our investigation clearly show, that the success of mandibular reconstruction mainly depends on a well vascularized transplant bed. The objective of this study was to evaluate the effect of omega-3 fatty acid supplementation on the rate of muscle protein synthesis in older adults.

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The relaxing effect of ligustilide on the NE- and CaCl2-induced constrictions is more potent than that of butylidenephthalide. In an ELISA, the HSA-bound particles and HSA molecules competitively reacted against the anti-HSA monoclonal antibodies. To describe the effects of human immunodeficiency virus (HIV) infection on the serologic manifestations and response to treatment of syphilis in intravenous drug users.

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The G6PD enzyme catalyzes the first step in the pentose phosphate pathway to protect cells against oxidative stress. A novel gene therapy approach for treating damaged cartilage is proposed that involves placing endotoxin-free cDNA containing the gene for bone morphogenetic protein-2 (BMP-2) in type I collagen sponges and then transferring the naked plasmid DNA construct to the injury site. Management consists of absolute rest and closure of the fistula.

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Pemphigus vulgaris is an autoimmune vesiculobullous disease of the skin and the mucous membrane. The early outcome in patients undergoing off-pump coronary artery bypass grafting: our experience. Isolation and characterization of a mitogen from pokeweek (Phytolacca americana). Dietary fat and cancer: rejoinder and discussion of research strategies. A control group of hearing bilinguals without any knowledge of ASL produced an entirely different pattern of results.

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Exposure and outcome variables as well as characteristics of their clinical course were identified and analyzed. Examples are derived from familial hypercholesterolemia, familial HDL deficiency/Tangier disease and familial hypobetalipoproteinemia. Measurements of positronium-formation cross sections for positrons scattered by Rb atoms. A total of 300 households from three villages making up Kiromo ward were included in this study. These data suggest that skin and airway responses to soybean components (particularly the non-lipid ones) are very frequent among soybean workers.

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It has been puzzled that in spite of its single-headed structure, myosin-IX shows the typical character of processive motor in multi-molecule in vitro motility assay, because this cannot be explained by hand-over-hand mechanism of the two-headed processive myosins. A cause and effect relationship between steroid hormones and hepatocellular carcinoma has been advocated in the literature.

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An appraisal of epidemiologic data concerning the effect of oxidants, nitrogen dioxide and hydrocarbons upon human populations. Mutational analysis of the estrogen receptor-alpha gene in familial ovarian cancer.

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Inclusion of FSH in the alginate bead restores the follicle growth response to FSH, while also providing a scaffold of support for three-dimensional growth. Here, the authors summarize results of published works in this field by using meta-analysis. Suicide and suicidal behaviour are increased in mood disorders, particularly bipolar disorders. However, in all studies showing recognition priming effects, encoding and rehearsal contiguity may have coincided with spatial proximity, and thus priming may have been due to temporal associations formed during rehearsal, not encoded spatial relations per se.

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Persistent organic pollutants in krill from the Bellingshausen, South Scotia, and Weddell Seas. Retrospective analysis previously identified significant elevation of five tumour markers, carcinoembryonic antigen (CEA), ferritin, orosomucoid.

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Marked differences in the expression of surface proteins, as determined by monoclonal antibodies raised against the first isolate, were observed. Artepillin C, a major, biologically active ingredient of Brazilian propolis, possesses anticancer activity against several cancer cells with different tissue origins. Survival outcome for elderly patients with newly diagnosed diffuse large B-cell lymphoma remains suboptimal in the rituximab era. For therapy assessment PET-CT scans, consistency in patient preparation, scanning and image reconstruction parameters, and image analysis are critical.

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We conclude that the epidermal nuclear staining reactions observed by direct immunofluorescence on skin biopsies is selective and that the penetration of IgG into the epidermal cell nuclei is an active process and not an artefact. In the present study we assess whether vitamin D supplementation, in the follow-up period after diagnosis and surgical resection of the primary tumor, has a protective effect on relapse of cutaneous malignant melanoma and whether this protective effect correlates with vitamin D levels in serum and Vitamin D Receptor immunoreactivity in the primary tumor.

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A peripheral lymph node biopsy confirmed the presence of a diffuse large B cell non-Hodgkin lymphoma. Hematoma volume is a powerful predictor of 30-day mortality in patients with intracerebral hemorrhage (ICH). Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy. After recovery of the fetus, the ovary-mesonephric complexes were immediately isolated, fixed and processed for histology. The presence of oncogenic types of HPV was tested for in samples taken from the cervix at colposcopy, and compared with detection by polymerase chain reaction (PCR) in 60 patients.

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It was found that exposure of podocytes to BSA induced podocyte apoptosis in a concentration-dependent manner that was accompanied by up-regulation of active caspase-3, the disruption of F-actin cytoskeleton, and decreased expression of CD2AP. To evaluate the long-term pharmacokinetics and safety of adding ritonavir 100 mg twice-daily to a nelfinavir 1250 mg twice-daily regimen in HIV-infected patients. Using a novel mechanism by which Dia1 mRNA is targeted to the perinuclear endoplasmic reticulum, we redirected the mRNA encoding Arp2, a subunit of the Arp2/3 complex, to the perinuclear region in fibroblasts.

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Voxel-based analysis of quantitative T1 maps demonstrates that multiple sclerosis acts throughout the normal-appearing white matter. To investigate to what extent antagonists of spinal neurotransmitters interact with the effects of sacral neuromodulation in a rat model of a chronically hyperactive urinary bladder.

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Predictors of Mediastinitis Risk after Coronary Artery Bypass Surgery: Applicability of Score in 1.322 Cases. Major advances are occurring in our understanding of the events leading to synapse formation.

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Physiologic replacement of insulin in patients with type 1 (insulin-dependent) diabetes following pancreas allograft transplantation results in normoglycaemia during fasting and postprandial states. This reorientation of helix III exposes several residues in the C-terminus and linker regions of S100B resulting in the formation of a hydrophobic patch surrounded be a number of acidic residues. The most frequently prescribed SSRI was fluoxetine and the PDDs were slightly more than the DDDs for all these SSRIs except fluvoxamine. With the dominance of cognitive behavioural therapies within mental health nursing educational and practice settings, a danger exists that a narrow application of therapy interventions and micro skills will result.

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Interaction among the base ingredients of the film was investigated using differential scanning calorimetry (DSC), powder X-ray diffraction (PXRD) and Fourier transform-infrared (FT-IR) spectroscopy. Second, the vomeronasal organ is primarily responsible for mediating responses to some, but by no means all, pheromone-like signals. Effects of electromagnetic fields in experimental fracture repair.

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The long-term safety and efficacy of primary stenting using drug-eluting stents (DES) in patients with ST-segment elevation myocardial infarction (STEMI) are not fully understood in Japan. Brief or prolonged mild hypothermia after arrest does not mitigate the postarrest cerebral O2 uptake/delivery mismatching. Expression of calpastatin, the endogenous inhibitor of calpain, was decreased in the CMV and low MP groups but its level was preserved to controls in the high MP group. Here we describe a method for routine isolation of adipose stromal cells, culture expansion, and characterization by differentiation and then production of conditioned media. Neuroserpin undergoes oxidative inactivation in glaucoma which leads to augmentation of plasmin activity.