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Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has become a crucial diagnostic technique for pancreatic malignancies. Electroencephalographic study on narcolepsy--with special reference to paradoxical sleep Therefore, the sensitivity of excitation and blocking thresholds of nerve fibers within a sacral root to geometric and electrical parameters in tripolar stimulation using a cuff electrode, have been stimulated by a computer model. We present here a 45-year-old male with no past medical problem who presented with palpitations. Genetic analysis of an XY newborn with hypospadias and micropenis.

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Corticosteroid-induced myopathy in spinal cord injury patients: a role for anticatabolic agents? Method of estimating the severity of regurgitation in mitral and aortic valve insufficiencies. The objective was to investigate trends in work-related mortality from cardiovascular disease (CVD) among seafarers employed in British merchant shipping from 1919 to 2005, to compare CVD mortality among British seafarers at work in British shipping - and ashore in Britain - with that in the general British population, and to investigate work-related CVD mortality in British shipping during recent years according to factors such as rank, nationality, location, and type of ship. You Look Human, But Act Like a Machine: Agent Appearance and Behavior Modulate Different Aspects of Human-Robot Interaction. Rapid, field-adapted indirect enzyme-linked immunosorbent assay for detection of antibodies in bovine whole blood and serum to Brucella abortus.

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The differences observed in ciliate abundance, and in prokaryote abundance and community composition in the two experiments were in accordance with these predictions. Leishmania donovani requires functional Cdc42 and Rac1 to prevent phagosomal maturation. A resurgence of pertussis has been observed in Canada, the United States and Australia since the 1980s, but inconsistent data are currently available for Europe. Elevated levels of plasma fibrinogen are a risk factor for cerebral infarction. Nucleotide preferences in sequence-specific recognition of DNA by c-myb protein.

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Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked overgrowth syndrome associated with multiple congenital anomalies caused by a mutant X-linked recessive trait. In specific developmental processes, cells of endodermal and ectodermal (non-neural) origin were also immunoreactive for these molecules. Possible interactions of the endothelial constitutive nitric oxide synthase genotype with alcohol drinking and walking time for high serum uric acid levels among Japanese. More important features of microcirculation during traumatic shock The abattoir condemnation of meat because of parasitic infection, and its economic importance: results of a retrospective study in north-eastern Iran.

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Policy and program-related efforts to increase physical activity in preschoolers should consider these patterns to leverage opportunities to optimize physical activity within ECE centers. Two reviewers independently verified study inclusion and extracted data. Serratia marcescens infection or hypoxic-ischaemic encephalopathy in neonates: Is magnetic resonance imaging a problem-solving tool?

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Validation of proteomic-based discovery with tissue microarrays. The purpose of this work is to compare, a conventional technique, for bacterial isolation, with a lysis-centrifugation method using a rapid freezing in liquid nitrogen, followed by decongelation at 37 degrees C for bone and joint samples. In the third patient the small intestinal defect was secondary to pernicious anaemia, and in a group of 98 other patients with pernicious anaemia intrinsic factor did not improve vitamin B(12) absorption in six, and only partially corrected absorption in 30. Second order perturbation theory, in conjunction with high quality ab initio electronic structure data, produces an approximately diabatic Hamiltonian whose eigenenergies and eigenstates can accurately describe the three adiabatic potential energy surfaces, the interstate derivative couplings, and the branching and seam spaces in their full dimensionality. Lipid-induced organization of a primary amphipathic peptide: a coupled AFM-monolayer study.

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Following an extensive search of peer-reviewed articles on the development of Mcl-1-selective inhibitors, the literature retrieved has been chronologically arranged for the large part and discussed in this review article. The purpose was to investigate how growth hormone exerts its stimulating effect on the healing of experimental colonic anastomoses. The United Kingdom spends less on health care than most other Western nations. Pretibial myxoedema (PTM) in its most extreme form clinically resembles lymphoedema.

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The amount of contact area born through the scaphoid fossa was essentially the same whether the scaphoid was intact, or after a simulated scaphoid fracture of its proximal pole, or after resection of the proximal pole. Strictures that have narrow or tortuous lumens can be particularly difficult to stent as the luminal diameter must allow access of at least a 0.035 inch guide wire. Step increases in sodium intake (20, 100, 400, and 1200 mmol per day), each maintained for 6 days, were administered as a fixed dietary (20 mmol) component with the balance infused intravenously. A novel delta 0 mutation in cis with Hb Knossos: a study of different genetic interactions in three Egyptian families.

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Overall, the patients who were treated at the Yad Sarah dental clinic expressed high levels of satisfaction with the care they received. CT follow-up half a year later showed complete resolution of compression of the spinal cord and complete recovery from myelopathy was clinically apparent. This doublet may be a more reliable indicator of acute infection than the 6 kilodalton band. Intrauterine congestive heart failure was thought to have been the probable cause of hydrops in eight of the 10 infants with endocardial fibroelastosis. RNA slot blot hybridization revealed that TPA induced the accumulation of P0 mRNA in FRTL-5 cells in a time- and dose-dependent manner.

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They were of intermediate to high nuclear grade and showed significant mitotic activity. Interestingly, drug treatment reduced the proportion of interdigitating cells staining with the monoclonal antibodies NLDC-145 and MIDC-8. To investigate the effect of preoperative radiotherapy as an adjunctive approach on proliferation and apoptosis of cancer cells in rectal cancer. Ultrastructural analysis of the GFP-labeled VMC axons confirmed the existence of synaptic contacts onto dendrites and somata of FN motor neurons.

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Spontaneous growth hormone secretion increases during puberty in normal girls and boys. Traditional oral antidiabetic agents, recommended as first- and second-line therapies in patients with type 2 diabetes inadequately controlled with diet/exercise or monotherapy, have limited durability of effect and are associated with an increased risk of adverse events.

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Recent studies on brain monoamine levels have shown that a lower 5-HIAA level does play some role in suicidal behavior, particularly violent suicide, although there is no predictive power for normality. Pretreatment the slices with DL-2-amino-5-phosphonovaleate (DL-APV, 50 microM) blocked the induction of LTP, indicating that N-methyl-D-aspartate (NMDA) receptor activation is required for induction. Cases of papillary thyroid carcinoma that lack marked nuclear enlargement, pale chromatin, and intranuclear inclusions are significantly more difficult to recognize than cases that have these features. MADS-box genes encode transcription factors that are key regulators of plant inflorescence and flower development.

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The path analysis approach for the multivariate analysis of infant mortality data. Methotrexate for steroid-resistant systemic lupus erythematosus.

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Clinico-enzymologic and morphological characteristics of the icteric form of infectious hepatitis in children in relation to the severity of the disease In addition, a brief overview of more general patient factors is included. In order to develop a mouse model of this disease and to further studies of hemostasis, thrombosis, and other suggested roles of beta3 integrins, we have generated a strain of beta3-null mice. Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing.

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Simulating a force-distance curve at low salt concentration predicts a discrete hopping of the tip, caused by thermal fluctuations. Endoscope-assisted Transoral Approach for Parapharyngeal Space Tumor Resection.

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Automatic interface-controlled apheresis collection of stem/progenitor cells: results from an autologous donor validation trial of a novel stem cell apheresis device. These suggest to prolong eradication therapy up to 14 days, replacing the old triple therapy with a quadruple therapy based on proton pump inhibitor (PPI), bismuth, metronidazole, and tetracycline for most of the patients, or as an alternative quadruple therapy without bismuth, based on the use of PPI, amoxicillin, metronidazole, and clarithromycin.

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These results provide a physiological demonstration of the cooperative interaction of Angptl1 and Angptl2 in endothelial cells through phosphatidylinositol 3-kinase/Akt mediated antiapoptotic activities. Drug hypersensitivity reactions: from clinical manifestations to an allergologic diagnosis. Changes of G1 cyclins, cdk2, and cyclin A during the differentiation of HL60 cells induced by TPA. Multiple logistic regression was used to assess the contribution of different variables.

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To determine glutathione peroxidase (GPX) and superoxide dismutase (SOD)-like activities in spermatozoa, seminal plasma, and reproductive tissues (ie, testis, epididymis, bulbourethral gland, prostate, vesicular gland, and ampulla) in horses. Special attention has been drawn to the choices for each separate graft or flap. Dissolution and nanoparticle generation behavior of Be-associated materials in synthetic lung fluid using inductively coupled plasma mass spectroscopy and flow field-flow fractionation.

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Six focus groups were conducted: four with African-American men and two with female significant others. Ginger (Zingiberis Rhizoma), a commonly-consumed food supplement, is often sulphur-fumigated during post-harvest handling, but it remains unknown if sulphur fumigation induces chemical transformations in ginger.

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The derivatives displayed an increase in the p27Kip1 protein in cyclin E/CDK2 immunoprecipitates and a decrease in cyclin E-associated kinase activity when compared to vector control clones, providing evidence that the overexpressed protein was functional. Detailed medical records and clinical evidence for 3290 deaths (mostly adults) among residents of six cities representative of the urban Chinese population were reviewed by a panel of physicians and coded by experts to establish a reference underlying cause of death. Quantum-mechanical treatment of high-energy channeling radiation.

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The distribution and abundance of heme oxygenase-1 closely matched that of axonal transport disruption, and encompassed hypoxic regions and their immediate penumbra. Geographic and demographic variability in 20-year hypertension incidence: the CARDIA study.

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The patient was initially recovered, but he died of heart failure caused by the recurrence in the left ventricle on the 5th postoperative month. The claustrum is topographically and reciprocally connected with many different cortical areas, and anatomical and physiological data suggest it is composed of functionally distinct subdivisions. A diagnostic laparoscopy was performed as appendicitis was suspected.

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The phase-separation conditions of n-butanol solutions were studied in the presence of commonly used inorganic salts. Immunohistochemical expression of Twist-1, E-cadherin and EZH2 in 50 specimens of prostate cancer and 20 cases of benign prostatic hyperplasia were studied.

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Establishment and evaluation of immortalized human epidermal keratinocytes for an alternative skin irritation test. (b) Does continued support for the home language undermine attainment in a second language? Effects of lobeglitazone, a novel thiazolidinedione, on adipose tissue remodeling and brown and beige adipose tissue development in db/db mice. Endothelial cell shedding of VCAM-1 was increased in ATMS2-stimulated human umbilical endothelial cells. To uncover the associations between serum markers of ECM metabolism and circulating microRNAs with RV morphological and functional parameters.

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We have determined the exon-intron organization of the human X-linked gene (FLN1) encoding actin-binding protein 280 (filamin), a ubiquitous protein that plays an important role in the mechanochemical activities of cells through its association with actin filaments and membrane components. The method helps adequately solve the principal refraction problem, specify the optimal eyeglass correction for patients with astigmatism. Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer. A commonly used simple spiking cell model is modified for extracellular current activation.

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The procedural dose-length product was 24 mGy-cm, and unadjusted and adjusted radiation doses were 0.34 (0.2, 1.8) and 0.82 (0.55, 1.88) mSv, respectively. This chapter will lay the foundation of more complex elements that will be described in the various following chapters. Likewise, the type of interaction of TDHL with dopaminergic and adrenergic agonist-activated sites is not suggestive of a competitive antagonism.

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Doppler examination of uncomplicated post-term pregnancies may identify patients with normal results as having a low risk of developing fetal distress during labour. Inhibition of L-type calcium channels by somatostatins in human neuroendocrine tumor cells of the gut. The zymogen of the protease that degrades small, acid-soluble proteins of spores of Bacillus species can rapidly autoprocess to the active enzyme in vitro. Participants consisted of 177 dyads with both sexes as patients and partners in committed, heterosexual relationships.

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Pharmacokinetic parameters were estimated by weighted non-linear least squares regression analysis using the WinNonlin computer program. High-dose atorvastatin did not show significant difference of MACEs in STEMI patients undergoing thrombolysis but showed significant improvement in immediate coronary flow depicted by ST-segment resolution. The relationship of blood lead concentration to stature was evaluated by examining data from a sample of 1454 Mexican-American children aged 5-12 y, derived from the data sets of the Hispanic Health and Nutrition Examination Survey (HHANES) conducted in 1982-1984. However, virus-neutralizing IgG1 and IgG4/7 in seminal plasma were not effective in preventing viral infectivity. Health status surveys and assessments typically obtain detailed information on specific physical health conditions.

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The highest rates were in Israeli-born Jews and in Jewish immigrants from Europe/America (significantly higher in the former than the latter). A majority of the recorded cells sensitive to local epinephrine responded to this substance with a decrease in activity. Therefore, we aimed to examine the whole-body distribution of donepezil (DNP) as an acetylcholinesterase inhibitor by means of 11C-DNP PET imaging, combined with the oral administration of pharmacological doses of DNP. Signals and nuclear factors that regulate the expression of interleukin-4 and interleukin-5 genes in helper T cells. Outcomes following kidney transplantation for patients with amyloidosis-associated end-stage renal disease (ESRD) have not been well characterized.