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Boceprevir (Ribavirin)

This medication is an antiviral used in combination with interferon to treat ongoing hepatitis C. Long-term hepatitis C infection causes liver swelling that can lead to serious liver conditions such as scarring, cancer, and organ failure. Boceprevir works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. However, this drug is not a cure for hepatitis C infection, and it does not prevent the spread of Hepatitis C to others through sexual contact or blood contamination (e. g. , sharing used needles). OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat severe acute respiratory syndrome (SARS).

Other names for this medication:
Ribavirin, Rebetol, Copegus, Alfater, Beclabuvir, Boceprevir, Daclatasvir, Daklinza, Dasabuvir, Elbasvir, Filibuvir, Hepcinat, Hepcvir, Incivek, Kipferon, Ledifos, Ledipasvir, Miravirsen, Multiferon, Olysio, Ombitasvir, Paritaprevir, Pegasys, Pegetron, Pegintron, Rebetron, Resof, Setrobuvir, Simeprevir, Sofab, Sofovir, Sovaldi, Sylatron, Technivie, Telaprevir, Veldona, Victrelis, Zepatier,

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A case of adenocarcinoma of the cervical oesophagus was examined by employing a battery of histochemical techniques and was demonstrated to arise from ectopic gastric mucosa. Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents.

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Body mass index and intake of refined sugars were directly associated with risk of gallstone formation, whereas physical activity, dietary monounsaturated fats, dietary cholesterol, and dietary fibers from cellulose were inversely associated with risk of gallstone formation. Data are reported on the use of single stranded conformational polymorphism (SSCP) analysis of the nuclear ribosomal second internal transcribed spacer (ITS2) of individual schistosomes from hybrid zones of Cameroon. Nausea and vomiting with use of a patient-controlled analgesia system.

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Further, positive correlations were hypothesized to exist across the temporal lobes. Attraction to the melon fly was lost with ortho, meta, or dimethoxy substitution of benzyl acetate, but the 3,4- and 2,5-dimethoxybenzyl acetates were attractive to the oriental fruit fly. Both BNP and NT-proBNP measures obtained from short of breath patients presenting to an emergency department may be predictive of one-year all-cause mortality independently of the baseline diagnosis of acute destabilized heart failure. The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage. The analysis was based on the archive materials of the Regional Unit for Control of Epidemics and Hygiene Promotion in Lublin.

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We hypothesized that elevated CO(2) would enhance the reproductive allocation of shaded, subordinate Ambrosia artemisiifolia L. Non responders to neoadjuvant chemoradiation for esophageal cancer: why better prediction is necessary. Consistent with the literature, workload, remuneration and performance appraisal were identified as perceived threats.

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Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritis. The current state of therapy is far from optimal and resources should be applied to studying therapeutic options for patients who have CLL with loss of p53 function. Functional osteoclast-like transformation of cultured human myeloma cell lines. Data were analysed to estimate energy and nutrient intake, to determine dietary adequacy, and to summarise the most commonly reported foods and the top food contributors to selected nutrients.

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To determine the effect of a nurse-delivered smoking cessation intervention for hospitalized smokers on smoking cessation rates and smoking cessation self-efficacy at 6 months after enrollment. Helicobacter pylori infection, atrophic gastritis, and pancreatic cancer risk: A meta-analysis of prospective epidemiologic studies. Minimum energy conformers of the ligand structures were superimposed and fitted to L-arginine and the nucleotides of adenine and guanine using a computational program. HIV/STI co-infections, syphilis incidence, and hepatitis B vaccination: the Buenos Aires cohort of men who have sex with men.

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Cranio-cerebral traumatism occupies the first place among the causes of lethal outcomes and invalidism of the population and is a serious social-economic problem. Gene expression variance was estimated by RefFinder, which integrates four different analytical tools. Although, some of these detection assays are not applicable to clinical use, it is now possible to measure a number of inflammatory mediators released from cells participating in allergic disease. The aim of this study was to evaluate the efficacy of SADBE on cutaneous warts by a randomized, double-blind, vehicle-controlled, clinical trial. In these astrocytes, CXCR4, MMP, and tissue inhibitors of matrix metalloproteinase mRNA expression and SDF-1alpha production were significantly up-regulated.

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Therefore, these patients require a personalised management approach discussed in a multidisciplinary meeting. Further studies are required to confirm that stricter air quality regulation or antioxidant regimen translate into some clinical benefits. The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11. Obesity has progressively become a global epidemic that constitutes one of the biggest current health problems worldwide. The performance of the CAP as compared with the US results was assessed using the area under the receiver operating characteristic curve (AUROC).

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A system for surgical audit, which has been developed during a 6 year period in an active surgical unit of a teaching hospital, is described. Closely related Wolbachia strains within the pumpkin arthropod community and the potential for horizontal transmission via the plant. The main difficulty of the study was to find quality data for generating expected values as input for the models. Cortical atrophy in the cerebellar variant of multiple system atrophy: a voxel-based morphometry study.

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Implications for public health: These findings have important implications for planning for aged care services, including the role of housing in delaying admission to residential aged care, and the need for residential care by a high proportion of women towards the end of life. Preferences of interns and residents for E-mail, paging, or traditional methods for the delivery of different types of clinical information.

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This article is the second of a two-part series providing an overview of the public sector financing plans for children who require pediatric services at home and in the community. We illustrate our methods using a dataset of patients with primary breast cancer.

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ModuleFinder identifies sets of genes and treatments that form useful sets for analysis of the mechanisms behind co-expression. Possible explanations for the differences found are discussed, including the role of oxygen-derived free radicals. Taken together these results suggest that homo- and heterodimerization are important for the activity of ADAR family members in vivo and that these associations are RNA independent. Scopolamine in the higher doses impaired maze performance on the test day, but methylscopolamine did not.

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This case report documents a rare case of a subgaleal pneumocele occurring more than 20 years after cochlear implantation. Forty-six patients with progressive metastatic GCTs were treated with paclitaxel and ifosfamide plus cisplatin (TIP) as second-line therapy. Foreign bodies are usually inserted as result of erotic activities, psychiatric disorders and, rarely, in an attempt to evacuate the urine.

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To investigate the potential developmental toxicity of Radix Ophiopogonis decoction in SD rats. We enrolled 111 patients in the TBI group and 126 in the non-TBI group.

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The availability of the drug information database Vidal on PDA and on tablet PC implied our choice of the database. Immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users. A UK birth cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC), were used to collect pet ownership data from the mothers, from gestation to child age 10 years old.

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Furthermore, the tumor invaded into the major branch of the portal vein (Vp3). Neutrophils contribute to the host defense mechanism, but they can cause remote organ injury in peritonitis. Multi-level spine endoscopy: A review of available evidence and case report. The Computer Speech Lab was used to record and perform acoustic analyses of the vowels /a/, /e/, /i/, through the vocal parameters: fundamental frequency, intensity, jitter and shimmer.

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pylori who tested urea breath test-negative at 8 weeks after treatment were followed prospectively at 4 months, 6 months, 1 year and 2 years. We present here the results of a simple algorithm to assign tissues in the human body to one of four categories: soft-tissue, hard-bone, trabecular-bone and porous-lung.

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Maxwell-Bloch equations: A unified view of nonlinear optics and nonlinear atom optics. Jacobson resonance, a general form of Zeeman and cyclotron resonance, is proposed as a fundamental explanation relating to the effects of non-ionizing radiation on biological systems. A degradation pathway for 2,4-DCP is proposed on the basis of detection of intermediate compounds. Gene transfer using retroviral vectors requires cell replication for insertion of the DNA provirus.

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This secondary reactive hemophagocytic syndrome, referred to as MAS in the current medical terminology, can be a complication either of the rheumatic disease associated syndrome (RAHS), or of the infection associated form (IAHS) and malignancy associated form (MAHS). The complex diagnostic procedure involved in determination of occupational allergic diseases is discussed.

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Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens. Of the 54 who underwent open surgery, 34 survived without any recurrence of disease, 1 currently has metastasis, 6 died of metastasis within 17 to 74 months, and 13 died without any disease recurrence. Inflammatory linear verrucous epidermal nevus (ILVEN) is a rather uncommon dermatosis that typically has an early age of onset, is unilateral, localized, pruritic and relatively refractory to treatment. Lineage commitment of Th cells is associated with the establishment of specific transcriptional programs of cytokines.

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Report of their coexistence and a survey of possible associating features. The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function. Expression of a truncated cDNA from which 81 base pairs (27 amino acids) of the upstream reading frame had been deleted, showed localization of the smaller form of bFGF alone in the nucleus. Characterization and correction of distortions in stereotactic magnetic resonance imaging for bilateral subthalamic stimulation in Parkinson disease.

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A 6-week-old girl presented with cutis laxa, emphysema, heart anomalies and a diaphragmatic hernia. Predictive dentistry: the Cornell Medical Index Health Questionnaire (general response) and dental findings.

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The grown structures are characterized by Raman, photoluminescence, and annular dark-field scanning transmission electron microscopy to determine their lateral compositional profile. We examined thirty-three patients treated with conventional-dose PEB (cisplatin 20 mg/m2 x 5, q3w, etoposide 100 mg/m2 x 5 q3w and bleomycin 15 mg/m2 q1w) and 21 patients treated with high-dose PEB (cisplatin 40 mg/m2 x 5 q3w, etoposide 200 mg/m2 x 5 q3w and bleomycin 15 mg/m2 q1w). The final stage of carcinogenesis, progression, can occur spontaneously, enhanced by formation and propagation of genetic errors due to increased cellular proliferation associated with the promotion stage. The increasing use of systemic adjuvant therapy even in lymph node-negative breast cancer patients and breast cancer screening programs detecting smaller tumors with less probability of metastatic lymph nodes questions the need for routine axillary lymph node dissection.

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The subject of electro-rheology is introduced to biological engineers in a concise manner to allow presentation of a procedure for effective quantitative evaluation of possible medical applications of this new technology. The inserted foreign DNA (lambda-gt10LacZ shuttle vector and/or pSVc-myc plasmid) was located at the middle of the long arms of chromosome 2 (lambda DNA) and/or chromosome 8 (c-myc). Proposal for a standardized ordinance for Italian schools of dentistry and prosthodontics An improved prognosis has been anticipated for young gastric cancer patients because of recent improvements in digestive tract diagnostic techniques. This reduction may be related to the requirement of endothelin signalling for the proliferation of ENS progenitors.

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A total of 48 consecutive patients with acquired immunodeficiency syndrome-related death underwent autopsy and had their eyes submitted for histopathological examination. Bangladesh has a unique opportunity to address hypertension now in order to prevent thousands of premature deaths and to accrue substantial net economic benefits within 6years. Effects of theophylline, 3-isobutyl-methylxanthine and 1,3-dipropyl 7-methylxanthine on cell-radiosensitization in comparison to caffeine tested by clonogenic survival assay, MTT assay, ELISA based apoptotic assay, flow cytometry, caspase-3 activity, TUNEL assay, and western blot analysis. Data were analyzed by one-way multivariate analysis of variance to ascertain if there was an effect of group on clinical and psychometric test scores.

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A Significant Breakthrough in the Incidence of Childhood Cancers and Evaluation of its Risk Factors in Southern Iran. RNA interference (RNAi), which can cause the degradation of any RNA in a sequence-specific manner, is a post-transcriptional gene silencing mechanism. Storage-related defects in the incorporation of acetyl-CoA derived from acetate and palmitate were observed.

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Transsphenoidal microsurgical therapy of prolactinomas: initial outcomes and long-term results. The ventricular tachycardia has a polymorphous appearance and is usually induced by antiarrhythmic drugs. A large set of single-frequency continuous-wave lasers oscillate by amplification in spatially separated gain media. Reported ELS is associated with smaller ACC and caudate volumes, but not the hippocampal or amygdala volumes. The results demonstrate that PAT may be used to detect the effects of drug abuse-induced brain activation.

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The method requires two separate potentiometric titrations of the binder solution with ANS in the absence and in the presence of sulphonamides. Immunohistochemical staining for ER, PR, Ki67 and Bcl-2 was performed on polyps obtained from two groups of postmenopausal women. Polyamines increased mitotic index of cells in root tips of regenerated plantlet cultured on medium containing 0.001 microM Put, Spd, or Spm, but did not increase mitotic index in tissues of needle tips of the same plantlets.

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The antioxidant melatonin reduces cortical neuronal death after intrastriatal injection of kainate in the rat. Is osteoporosis a peculiar association with primary biliary cirrhosis? However, until now RhoA function in the ESCC progression remains to be established. With appropriate measures of patient selection, surgery can provide an efficacious option for geriatric patients with type II odontoid fractures.

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Our results suggest that HHV-6A and HHV-6B have different tropism in MO3.13 cells and that an initially active HHV-6A infection can develop latency. Mitral valve replacement in idiopathic eosinophilic endocarditis without peripheral eosinophilia. Comamonas acidovorans (Pseudomonas acidovorans) is a ubiquitous gram-negative rod. Additionally, one should be aware that amblyopia is common especially in the patients with associated strabismus and/ or anisometropia. Participants in the Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) study underwent screening assessments (anthropometry, BP, OGTT) and were stratified into normal BP (NBP), prehypertension, or hypertension, and normal glucose regulation (NGR), prediabetes (IFG/IGT), or type 2 diabetes (T2D) status.

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It is widely controlled by antibiotic use, but this practice that has come under increasing scrutiny and alternative approaches are required. An additional analysis showed that the variance in fluid intelligence that was attributable to processing speed was not fully shared with the variance attributable to frontal function. The lack of social security and health insurance for the large majority of the population, however, is a serious limitation.

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One-hour recordings were made once a week between the 7th and 17th week of gestation. He was discharged with no neurological deficits 3 days after surgery. The present study investigated the hepatoprotective role of zinc in attenuating the toxicity induced by chlorpyrifos in rat liver. Clinical manifestations and prevention of radiation injuries to the teeth, mouth and jaws Prazosin (alpha 1-adrenergic receptor antagonist) partially blocked both DEX and PCP.

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Both treatments resulted in cardiac hypertrophy, but only isoproterenol induced significant increases in beta-adrenergic receptor kinase-1 protein levels and activity. Plasmatic retention of BSF and biliary flow at different intracanalicular biliary pressures

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Methylglyoxal levels in plants under salinity stress are dependent on glyoxalase I and glutathione. Production of AFMK was highly dependent on superoxide but not hydrogen peroxide. Lindane is readily absorbed through the skin, especially damaged skin and in children.

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We also have identified a residue in NovJ that when mutated results in a 50-fold reduction in catalytic activity. Patent applicants in this field are encouraged to be aware of these concerns when developing valid patent strategies.

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To elucidate the involvement of the human subthalamic nucleus (STN) region in the processing or transmission of emotional information. The 10 best presentation at the 29th national conference of the Spatinsh Society of Emergency Medicine (SEMES) Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital.

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A spectrum of disease was described ranging from a mild allergic rhinitis limited to periods of wheat dust exposure through to perennial asthma in which wheat dust was but one of several precipitating factors. Perampanel with concomitant levetiracetam and topiramate: Post hoc analysis of adverse events related to hostility and aggression. Improving the psychiatric and social support can reduce the incidence of self-harming behaviour, its repetitiveness and subsequently the cost of burn care. Hypotensive shock and angio-oedema from angiotensin II receptor blocker: a class effect in spite of tripled tryptase values. That foldons are the critical targets of mutation studies has notable implications for design strategies and is of particular interest to address the issue of the kinetic regulation of single proteins in the duoplavin fda approved general context of the overall dynamics of the interactome.

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The ratios of individual serum hormone concentrations during pregnancy relative to their 1-year postpartum concentrations illustrate the expected normal trends of changes in hormone concentrations during pregnancy. It is an interdisciplinary specialty in which scientists apply the study of genetics in conjunction with traditional ecological fieldwork and other techniques to explore molecular variation, population boundaries, and evolutionary relationships with the goal of enabling resource managers to acyl carrier protein functional assay better protect biodiversity and identify unique populations. In this study, we investigated the mechanism by which murine dendritic cells mediate the apoptotic death of murine lymphoma cell lines, and whether dendritic cell effector function could be enhanced by preconditioning tumor cells with the protein phosphatase inhibitor nitric oxide (NO) by altering the balance of proapoptotic/antiapoptotic proteins in the treated cells.

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After an indolent presentation and late diagnosis, the patient underwent surgical debridement with IV antibiotic management. Impact of high-frequency stimulation parameters on the pattern of discharge of subthalamic neurons. We highlight the power provula clomiphene citrate 50mg cost of Biomimetic Virulomics by capturing known virulence factors in a high-throughput, cell-type guided fashion. Aging and negative affect: the rise and fall and rise of anxiety and depression symptoms.

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The c-jun oncogene is frequently overexpressed in non-small-cell lung cancers (NSCLC), but its functional involvement in lung cancer development has not been clearly elucidated. Recent evidence suggests a shared derived characteristic that may be responsible for the retention of the organelles in the absence of the better-known mitochondrial functions--iron-sulfur cluster assembly. Methionyl aminopeptidase from rat liver: distribution of the membrane-bound subcellular enzyme. Application of a new morphometry system based on prinivil side effects cough SEM stereo-pairs to the study of intestinal mucosa of rodents.

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Delirium has been well defined and reported as a significant problem in populations of patients receiving palliative care. Previous studies on this enzyme only focused on the transcriptional expression of this gene. The low agreement on health and treatment priorities between patients and physicians necessitates better communication between the two parties to strengthen mutual understanding. We report a rare case lambipol effects secondaires of closed rupture of both flexor digitorum profundus (FDP) and flexor digitorum superficialis tendons in zone II in the small finger.

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After an initial decline in respiratory state and motor function until 1-2years of age, residual capabilities reach a plateau. All patients underwent computed tomographic scans bisoprolol 5 mg pret of both thighs immediately before and after the 7-day treatment period. From January 1995 to December 1997, 648 consecutive cases of colorectal carcinoma were recorded at the Department of Surgery, National Cancer Center Hospital, Tokyo, Japan. Muscle fatigue may precede weakness as an early symptom of myopathy.

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Perfusion CT shows promise as another functional imaging modality but further experience with this technique is necessary before it can be applied to routine clinical practice. Standard T1-weighted MR images enhanced with gadopentetate dimeglumine show relatively minimal enhancement of breast lesions due to the high background signal from benidipine vs amlodipine dosage fat in the breast. A high molecular weight and low content of glycolic acid produced a slower and longer release.

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The ranking can be used either as a guidance to facilitate the manual beam placement or as prior information to speed up the computer search for the optimal beam configuration. Pediatric patients seeking treatment for chronic back pain often present with substantial functional impairment that is not well explained by disease variables or pain intensity. Application of aspiration cytology in the diagnosis of tumor lesions in children The inability of these structurally distinct ANF R1 receptor antagonists to prevent the neuromodulatory effects of ANF suggests the involvement of ANF R2 (clearance) receptors or another unidentified ANF receptor in mediating the response. Protease-monitoring systems have been introduced in industry, but have not been applied to domestic settings, probably because of recamicina 500 mg levofloxacino de 500 the high cost and many complex steps involved in these systems.

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Cells with enfeebled endocytosis and vacuolar protease activities prevented edelfosine-mediated (i) mobilization of lipicard medicine wheel sterols, (ii) loss of Pma1p from lipid rafts, and (iii) cell death. Ketamine, a glutamate noncompetitive NMDA receptor antagonist, regulates excitatory amino acid functions, such as anxiety disorders and major depression, and plays an important role in synaptic plasticity and learning and memory.