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This article presents current knowledge of clinical effects and adverse drug reactions of ephedrine in infants and children, and discusses the practical implications of these findings. The risk factors for abruptio placenta were chronic hypertension, recurrent vaginal bleeding, previous delivery with caesarean section and low socio economic status. We present evidence that stimulation of the human beta-3 adrenergic receptor (AR), expressed in Chinese hamster ovary/K1 cells, specifically activates the mitogen-activated protein kinases extracellular signal-regulated kinase (ERK)1 and 2, but not JNK or p38. In cases of low-grade astrocytomas, stereotactic guided surgical removal has low morbidity. We review the pathophysiology and clinical features of this involvement with the presentation of our experiences.

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