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Flexiplen (Diclofenac)

Flexiplen is used to relieve pain, swelling (inflammation), and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. Flexiplen is known as a nonsteroidal anti-inflammatory drug (NSAID). Misoprostol protects the stomach from Flexiplen's irritating effects. This combination medication is used to treat arthritis in people at high risk of developing stomach ulcers and serious complications such as bleeding. If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat gout attacks.

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A sample of 109 patients who received dental care between 3/01-3/02 at the Yad Sarah dental clinic in Jerusalem were asked about : their satisfaction concerning their experience of previous visits, the frequency of their visits, how they heard about the clinic and whether they would return to the clinic in the future. The lowest endotoxin concentration that consistently gelled at 20 min was 4 EU x ml(-1) . In this respect diagnostic measures and clinical symptoms are reported. Understanding the cultural, ethnic, and socioeconomic factors in a postdisaster situation is crucial to helping special populations overcome debilitating mental illness and declining quality of life. We propose that levels of IgE normally present in mice favour immune sensitization via antigen-independent effects on mast cells.

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Several double-blind randomised placebo-controlled trials have proven that risperidone is effective in attention-deficit and disruptive behavior disorders in children and adolescents, in behavioral problems and subaverage intelligence and in tic disorders. Biochemical hepatic alterations and body lipid composition in the herbivorous grass carp (Ctenopharyngodon idella) fed high-fat diets. During hospitalization, there was a significant deterioration in the scores given for all domains of the functional QLQ-C30 scale, but not the symptomatic scale. Aberrant HH signaling within GNPs is thought to give rise to medulloblastoma (MB) - the most commonly-observed form of malignant pediatric brain tumor. Finally, several medical implications of such intriguing event are presented.

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Here, the mode of action and biological role of intracellular FGF-2 are discussed. Binding sites for VIP in the reorganizing mucosa of the irradiated bowel. Current concepts on coronary revascularization using BRS in patients with diabetes and small vessels disease. Using confocal fluorescence microscopy, we determined that caveolin-1 and GM(1) colocalized, while Pgp and caveolin-1, or Pgp and GM(1), did not.

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Fused PET/CT is a valuable imaging tool in patients for staging diagnosis of NPC. It was feasible that all of the four models in 611-680 nm characteristic band are feasible to be used to predict, while the model accuracy of BP neural network and support vector regression was better than one-variable linear regression and multi-variable regression, and the accuracy of support vector regression model was the best. Autopsy revealed acid fast bacilli in the setting of numerous, bilateral, necrotic, granulomatous, cavitary pulmonary lesions. This contrasted to the saline control group in which active inflammation was accompanied by extensive areas of necrosis but with less fibrosis in the lungs and spleen.

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We carried out a retrospective analysis on patients with second MTPJ instability for which the FDL transfer was done as the primary procedure between 1996 and 2001. Neurotropism is a defining characteristic of alphaherpesvirus pathogenicity. HPS3 associates with clathrin, predominantly on small clathrin-containing vesicles in the perinuclear region.

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These findings indicate that MST1/STK4/Hippo signaling restricts aggressive tumor cell growth by intersecting with multiple molecular pathways, suggesting that targeting of the STK4/Hippo pathway may have important therapeutic implications for cancer. Masai barefoot technology has never been documented in detail concerning changes in movement pattern or muscle activity. Interactive virtual presence between certified CPS technicians and the public via smartphone app has potential to improve proper child restraint installations broadly, including to vulnerable and underserved rural populations. Characteristics of the trunk structure of the branches of the trigeminal nerve How familiar are you with the injury patterns specific to this increasingly popular sport?

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We present a case of a liveborn male with complete trisomy 1q in mosaic form due to a de novo unbalanced translocation. 3-Desacetyl-vecuronium is an active metabolite of the neuromuscular blocking agent (NMBA) vecuronium, which might lead to residual paralysis after prolonged administration of vecuronium in critically ill patients with renal failure. To emphasize the importance of mixing and chemical reaction, these coastal aquifers are called subterranean estuaries. Likewise, the phagocytosis of IF1-treated PMNs was diminished when S. Up to three 24-h dietary recalls were collected on nonconsecutive days, capturing weekday and weekend consumption.

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The possible involvement of other factors, including genetic variants, has been considered. Powerful postures versus powerful roles: which is the proximate correlate of thought and behavior? All mutant enzymes exhibited the same mobility on SDS-polyacrylamide gel electrophoresis as the wild-type enzyme and gave similar circular dichroism spectra to that of the wild-type enzyme.

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Accurate staging for gastric cancer is possible with the availability of sophisticated imaging studies, endoscopic ultrasound, and laparoscopy. Healthy male C57BL/6J wild-type mice (C57 mice) and apolipoprotein E knockout mice (ApoE mice) were randomly divided into six groups: C57 control group (sham operation, neither BCCAO was performed nor pharmacologic intervention was given), C57 ischemia group (BCCAO for 17 minutes was performed and normal saline was given intraperitoneally), C57 lidocaine group (BCCAO for 17 minutes was performed and lidocaine was given intraperitoneally), ApoE control group (the same procedure as that of C57 control group), ApoE ischemia group (the same procedure as that of C57 ischemia group), ApoE lidocaine group (the same procedure as that of C57 lidocaine group).

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To facilitate the study on this topic, we constructed two databases (DCCP and DICP) containing the known copper- and iron-chelating proteins, which are freely available from the website Although there are several surgical methods for treatment of sacrococcygeal pilonidal sinus, there is no widespread consensus. First, we performed a dose-finding study and found that 30 islets just failed to cure diabetic mice. We must now evaluate the usefulness of this classification for the treatment of men with LUTS. However, no review of the literature focusing on study findings of preferred music on agitated behaviours in older people with dementia had been reported.

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The creatine kinase-MB, a relatively specific cardiac marker, could be elevated in situations other than acute myocardial infarction, such as renal failure, muscular injury, and myopathy. Ethanol exposure was accompanied by an increased cellular iron uptake, together with increased expression of genes involved in iron transport and storage such as l-ferritin, Divalent Metal transporter 1, transferrin, transferrin receptor 1, and ceruloplasmin. However, at relatively high concentrations, the increase in osteoclast progenitors did not lead to increased resorption, since the putative osteoclast progenitors were arrested in the periosteum. It is characterised by an alteration of the vertical and horizontal dimensions of the breast, which is translated into a lack of development of the breast and into the herniation of the glandular tissue within the areola with hypertrophy of the latter.

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However, experiments using compartmented cultures of rat sympathetic neurons have shown that neurite growth is a local response of neurites to NGF locally applied to them which does not directly involve mechanisms in the cell body. A growth inducer newly identified in our screen of neural stem cells (NSCs) has potent inhibitory activity against dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) and was found to rescue proliferative deficits in Ts65Dn-derived neurospheres and human NSCs derived from individuals with DS. Levels of CRP in combination with PCT is a reliable index for determining the existence of bacterial infection, which is of great clinical guidance significance to the treatment and prognosis assessment of AECOPD patients. Resonance contributions to anti-Stokes/Stokes ratios under surface enhanced Raman scattering conditions.

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EIV-specific immunity was stimulated by vaccination with a recombinant vaccine as serological responses were detected after immunisation. These new data strengthen the hypothesis that molecular components of the circadian system play a central role in the generation of sleep and wakefulness beyond just the timing of these behavioral vigilance states. Additional therapies to decrease ischemic events in patients with established vascular disease or at risk for developing vascular disease are necessary. A mini meta-analysis of these studies showed that all participants were more likely to link the experience of shame to suicidality than guilt.

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Next came the production of heroin and other synthetic opioids, along with increases in nonmedical use of prescription medications. 13-Alkyl derivatives (2-6 and 8-12) of berberine (1) and palmatine (7) were subjected to in vitro antibacterial activity tests against Bacillus subtilis and Salmonella enteritidis. The braided structure and organic microtubule reinforcement phase are responsible for its high mechanical performance.

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GROUP R: After about two weeks the allografts were completely opaque, which was accompanied by a massive leukocyte infiltration in conjunction with EC destruction, signifying rejection. Convincing evidence for association was found only for the intake of alcohol and whole grains in relation to colorectal cancer risk. Combined radiotherapeutic and surgical management of a spinal cord compression by extramedullary hematopoiesis in a patient with hemoglobin E beta-thalassemia. Adventitious embryony and apomictic seedlings would explain the mostly clonal populations suggested by molecular studies. Thus, measurements of rectal epithelial proliferation (REP) could be useful as a screening biomarker of risk for sporadic neoplasia.

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In addition, within each of the two lineages of filarial wolbachiae, the phylogeny of the symbionts is consistent with the host phylogeny. A heterodyned fifth-order two-dimensional (2D) IR spectrum of a model coupled oscillator system, Ir(CO)(2)(C(5)H(7)O(2)), is reported. When it comes to the placement of these changes, they were mostly located in the labial surface of incisors of the maxilla, less frequently in the canines and premolar teeth. These findings support our hypothesis that there is inadequate knowledge and awareness about hepatitis B infection in the general population in Hong Kong. Northern blot analysis with a cDNA probe specific for human tissue-type transglutaminase showed that exposure of HepG2 cells to IL-6 increased the mRNA level of the enzyme, and the increase was detectable 3 h after IL-6 was added.

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Benign chest wall mesenchymoma in children is an extremely rare disease. Molecular characterization of cell-free eccDNAs in human plasma. Metabolic differentiation of early Lyme disease from southern tick-associated rash illness (STARI). Emergence of epidemic clones of vancomycin-resistant Enterococcus faecium in Singapore.

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Elongation factor-1 (eEF1), which is responsible for aminoacyl-tRNA transfer on the ribosome, is comprised of two entities: a G-protein named eEF1A and a nucleotide exchange factor, eEF1B. Transplantation of islets using microencapsulation: studies in diabetic rodents and dogs. Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length. The study suggests that the endogenous CCK satiety effects appear early in the second week of postnatal life in normally nourished rats, whereas in undernourished rat pups it does not appear till day 20-22. Neuroendocrine differentiation has been demonstrated by immunohistochemical preparations in many cases of acinar type prostatic adenocarcinoma (CAP).

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Altogether, our findings uncover new facets of Kappa physiology, whereby this receptor may be epigenetically regulated by stressful experiences, in particular as a function of early social life. Multiplexing technologies based on the use of microspheres as the solid phase have opened new possibilities for the analysis of autoantibodies. The purpose of the study was to examine the relationships between the status of subclinical thyroid conditions and cognition among adolescents in the United States.

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Temporal trends between 2010 and 2015 in intensity of care at end-of-life for patients with chronic illness: Influence of age under versus over 65 years. The relationship between topiramate (TPM) concentration, dosage and adverse events in patients with epilepsy is still controversial. Evaluation of a bioactive glass alloplast in treating periodontal intrabony defects. Colorectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease. In addition, we discuss the potential of the CGL1 model system to investigate the effects of near zero background radiation levels available within the radiation biology lab we have established in SNOLAB.

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Our study showed that well-directed violent and self-destructive behavior was not a feature of epileptic psychosis in general but a specific hallmark of postictal psychosis. Moreover, we provide the first description of rxfp1 spatial expression pattern during embryo development, showing that the transcript is already present at the early developmental stage and is distributed in all of the embryonic cells until somitogenesis.

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Use of an erythrocytic Vi diagnostic agent to detect chronic typhoid carriers. SGBS is also associated with an increased risk of developing embryonal tumors, mostly Wilms and liver tumors. X-ray television macrofluoroscopy and its resolution (studies on x-ray television. Orbital exenteration is a psychologically and anatomically disfiguring procedure reserved for the treatment of potentially life threatening malignancies or relentlessly progressive conditions unresponsive to other treatments. The microwire arrays are made by stack-and-draw fiber fabrication technique using multi-step co-drawing of low-melting-temperature metals or semiconductor glasses together with polymers.

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The mean BCVA and SD-OCT central subfield thickness (CST) values were determined at each time point. Extracellular vesicles (EVs), including exosomes are endocytically derived nanovesicles expelled from cells that contain molecular information in the form of lipids, proteins, and nucleic acids. Herein, we aim to raise the awareness of the overall common design and working principles of catalysts incorporating aspects of biology, chemistry, and material sciences.

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Histomorphologic considerations on the so-called fibrous osteodysplasia of the jaw Comparative analysis of primary cell lines by 2-DE found 43 proteins up-regulated and 29 down-regulated in at least three out of five tumour cell lines. This variation in entry criteria might lead to the selection of patients with different characteristics. Comparison was made with patients undergoing conscious sedation ERCP (sedERCP). Cytochemical demonstration of lysosomes in exfoliated epithelial cells of the gingival cuff.

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We find that the through-space electron transfer leads to (i) the enhancement of the bending IR peak at 135 cm(-1) and (ii) the appearance of a new low-frequency peak around 50 cm(-1), thus resulting in a good agreement with the experiment. Passive vs active exposure and other variables related to the occurrence of hand adaptation to lateral displacement.

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These iterative optimizations are synchronized by planning the same experiments for all scenarios. Significant anti-tumor effects were demonstrated following treatment with both Imatinib and Sunitinib. The acid-base abnormalities reflect not only the ketoacidosis, but also associated extracellular fluid volume depletion, alcohol withdrawal, pain, sepsis, or severe liver disease. Inclusion criteria included articles published in (1) English, (2) human subjects, (3) between the years 1980 and 2010, (4) minimum of 24-month follow-up, (5) measures of clinical and functional outcomes, and (6) isolated grade III PCL injuries.

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We have sought to define the specific alterations in function and phenotype that occur in the KC after biliary obstruction. Together with that of obesity, the prevalence of non-alcoholic fatty liver disease is increasing.

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To do so, clustering and switching were assessed during semantic (animal, food/drink) and phonemic (S, F) fluency tasks. The GABA response mimics a short-latency, chloride-mediated inhibitory postsynaptic potential (IPSP) evoked in PNs by electrical or odor stimulation of afferent inputs, and the classical GABAA receptor antagonist bicuculline methiodide (BMI) quickly and reversibly blocks this IPSP.

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Moreover, the efficacy and time requested to eradicate the same strain from lungs was determined after intratracheal infection of guinea pigs. Thirty-five computer office workers (aged 18-55 years) participated in the study. The amount of the lowering of the water-ice transition depends on the nature of the sample and is highest in poultry breast and lowest in vegetables. Xenotropic and polytropic murine leukemia viruses (X-MLVs and P-MLVs) cross-interfere to various extents in non-mouse species and in wild Asian mice, suggesting that they might use a common receptor for infection.

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These results implicate androgens in regulating distinct features of complex motor output in a precise and nonredundant manner.SIGNIFICANCE STATEMENT Vocal plasticity is linked to the actions of sex steroid hormones, but the precise mechanisms are unclear. Type IV collagen was detected in microvessels only from the 9th GW onward. Northern blot analysis demonstrated marked expression of AM mRNA in mouse adipose tissue.

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To examine factors affecting energy intake and weight gain during EN in relation to disease site and nutritional status. Growth retardation is a common complication of chronic kidney disease (CKD) in children. The pcDNA-FABP-transfected cells expressed full-length L-FABP mRNA, which was absent from vector-transfected control cells. The strain AC-57 was isolated from the soil collected in the Shanghai suburbs. Mainly, we discussed the biosynthesis pathway of arachidonic acid, the key enzymes, the construction of transformation system and the genetic modification.

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Because macrophages are also involved in the immune response towards L. Primary care providers are crucial to the treatment initiation process and should be involved in future interventions to improve early detection and treatment commencement amongst patients with anorexia nervosa. A substantial number of dermatologists admitted to witnessing cases of hypersensitivity to CVF. Predictive Factors of Late-onset Rectal Mucosal Changes After Radiotherapy of Prostate Cancer. While these cyclic structures have immense diversity and potential in different applications, their direct analysis in biological buffer systems requires intensive sample preparation steps such as salt cleanup, extraction with organic solvents, and chromatographic separations.

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The elucidation of their specific effects and interactions will accelerate the development of novel therapeutic interventions against cancer development triggered by inflammation. Hypertrophic lichen planus (HLP) is a rare inflammatory skin condition and develops into squamous cell carcinoma in few cases. Infection is a well-known trigger for Sweet syndrome, but this entity has, to our knowledge, never been described after Mycoplasma infection. Moreover, additional prognostic factors seem to be necessary to improve the prediction of intracapsular tumor aggressiveness and the definition of patient subgroups at high risk for metastases. Except for CMA3, none of the comet parameters showed significant correlation with fertilization rate.

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Quality control in haematology: report of interlaboratory trials in Britain. With TGF beta 1 present, the capacity of cells in the DE to synthesize collagen increases with time, over a two-week period.

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Use of transillumination technique is not limited to venous cannulation only! A bioavailability model for tumor induction by nickel has been proposed, based on the results of animal inhalation bioassays conducted on four nickel-containing substances. Using pharmacological and molecular tools, we have determined that a PDE3 is the enzyme involved in the control of cAMP levels in the oocytes.

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Data management involves the collection, archiving, analysis and reporting of data. This algorithm was applied to three different TLPD samples (369 teeth) gathered retrospectively by nine periodontist, associating several intervals of probability with the corresponding survival rates, based on significant differences in the mean survival rates.

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However, it remains unknown whether foraging for social resources also obeys such a strategic principle. This study also confirms that chemotherapy improves the distant metastasis control rate in NPC.

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Secondary outcomes include postoperative pain, daytime sleepiness, speech and swallowing problems, weight and diet, narcotic use, and analogue snoring scale. Obtaining optimal performance from each strategy required modifying the naive off-the-shelf implementations of the algorithms to exploit the particular symmetry and sparseness of the sinogram-restoration problem. It was shown that the hydrolysis of these mixed lipid vesicles occurs in the scooting mode in which the enzyme remains tightly bound to the interface and only the substrate molecules present on the outer monolayer of the target vesicle became hydrolyzed Thus the phenomenon of scooting mode hydrolysis was not restricted to the action of PLA2 on vesicles of pure anionic phospholipids, but it was also observed with vesicles of zwitterionic lipids as long as a critical amount of anionic compound was present. Acylfulvene is 100-fold less toxic in vitro and in vivo than illudin S but possesses marked antitumor efficacy in vivo, thus displaying opposite properties from illudin S.

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Idiopathic myelofibrosis and secondary myelofibrosis in chromic myeloleukosis The epidemiological characteristics of TBE in the Balkans are not well known. Role of the induced dipole moment in the collisional interference in the pure rotational spectrum of HD-He and HD-Ar.

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We used a high-resolution measuring device to explore spatial micromovements of a diaphyseal and a metaphyseal fixating revision stem. In addition, underlying cerebral amyloid angiopathy may have contributed to the initial nonclassical edema distribution by compromising autoregulatory blood flow mechanisms. In couples with a normal semen analysis undergoing IVF/ICSI, the 3PN rate may serve as a surrogate marker of oocyte quality and may be altered by adjusting the stimulation protocol. However, the effect of varying aliasing velocity on the accuracy of this method has not been investigated fully.

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Further studies are needed to define dosing, duration and long-term clinical outcome. The prevalence of sucking habit and its relationship to malocclusion. Versican is a large (1-2 x 10(6) Da) chondroitin-sulfate proteoglycan that can form large aggregates by means of interaction with hyaluronan and also binds to a series of other extracellular matrix proteins, chemokines and cell-surface molecules. Purification and crystallization of recombinant Escherichia coli malate dehydrogenase. Fluorescence properties of particles obtained by digitonin fragmentation of spinach chloroplasts.

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Pyomyositis ipson forte comprimidos masticables is a relatively uncommon infection in temperate climates, and is often considered late in the diagnostic workup. When more data are available, it will be possible to evaluate the relationship between survival and specific MECP2 mutations.

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As speciality, the diagnostic bisoprolol-ct 2 5mg filmtabletten nebenwirkungen tamoxifen step by step scheme comprises in addition to the clinical case history a detailed exposure (occupational) history, lung function testing, assessment of nonspecific bronchial hyperresponsiveness, allergological diagnostics (skin prick test, measurement of specific IgE antibodies), privation and reexposure test and as gold standard specific bronchial challenge tests. To develop a decision forest for prediction of laser refractive surgery outcome. Study of standard tooth morphology for carving posterior tooth crowns by contour method

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