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Three infants did not receive antibiotics and died of GBS sepsis by 10 h of age despite mechanical ventilation and fluids for blood pressure support. The recent pharmacy education for 6 years in Japan is likely to orient pharmaceutical care practice for contribution to the treatment of patients by appropriate management of medication. By the end of dialysis, the PNa typically approximates the prescribed dialysate sodium (DNa), the difference between DNa and PNa being considered the sodium gradient. The results indicate that further investigations are necessary to assess the clinical importance of this metabolic system. Actions of growth hormone: enhancement of insulin utilization with inhibition of insulin effect on blood glucose in dogs.

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ChIP-on-chip analysis reveals angiopoietin 2 (Ang2, ANGPT2) as a novel target of steroidogenic factor-1 (SF-1, NR5A1) in the human adrenal gland. Regional gastrointestinal absorption of the beta-blocker pafenolol in the rat and intestinal transit rate determined by movement of 14C-polyethylene glycol (PEG) 4000. Cardiovascular, neuropeptide Y, and adrenergic responses in stress are sexually differentiated. A two-way (caffeine dose x restraint) analysis of variance revealed an overall effect (reduction) of restraint and caffeine exposure on maternal body weight gain and food consumption on gestation Days 9-11.

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Photoswitching of the intramolecular magnetic interaction was demonstrated using diarylethenes with 2,5-bis(arylethynyl)-4-methyl-3-thienyl side group. In chapter one, the methods used in the clinical studies are reviewed.

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Semantic category-based decoding of human brain activity using a Gabor-based model by estimating intracranial field potential range in temporal cortex. A history of UTIs is the only identified risk factor identified in this study which is associated with a significant increased risk of neonatal nephrocalcinosis and/or renal calculi.

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The aim of the study was to develop a sensitive detection method of Fusarium culmorum contamination in cereal samples. Moreover, our data suggest that these two lipid-modified protein fusions are dynamically targeted both to overlapping as well as distinct lipid-enriched compartments within cells. In this work, we employ extensive molecular dynamics simulations to study thermal transport in large suspended polycrystalline graphene samples.

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Posterior fossa cysts: supratentorial shunt placement with ultrasound guidance. Both adolescent mothers partnered with adult men and adolescent mothers partnered with male peers reported sexual abuse perpetrated by family members, family friends, strangers, and peers. pneumophila to overcome TLR2 dependent immune responses are discussed in this review article. We have shown that treatment with the KATP channel agonist pinacidil increases survival of bees while decreasing viral replication following infection with FHV, whereas treatment with the KATP channel antagonist tolbutamide decreases survival and increases viral replication.

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The aim of this study is to determine the correlations of plasma soluble CD36 concentrations with carotid intima-media thickness (IMT) and cognitive function in patients with type 2 diabetes. A pool of extramitochondrial frataxin that promotes cell survival.

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Applications on CCLE and GDSC databases show that HARF outperforms traditional Random Forest when the average drug responses of cancer types are different. In general, the pond habitat is characterized as a spatially and temporally highly unpredictable habitat, while streams provide more stable and predictable conditions for the development of larvae. Six novel PTCH mutations were identified in 6 out of 8 cases (2 sporadic and 4 NBCCS-related OKCs).

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We pursue integrated diagnostic quality MRI functionality with radiotherapy systems to boost the possibilities of image guidance by providing images with superior soft-tissue contrast during treatment. Although this was a preliminary study, age was not a significant prognostic factor for esophageal cancer patients in the non-surgery group, and making the external dose more than 60 Gy appears to be effective for improving survival of elderly as well as younger patients.

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In the SCN, 5-HT content correlated positively with motor activity, consequently correlated negatively to the free-running period at 3 out of 4 sampling times over 24 h but no such correlation was observed in other monoamines and their metabolites examined. These improvements have major impacts on reducing the cost of care even when costs for implementation, and investment in time for personnel and training is accounted for.

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Selecting appropriate patients who would benefit from CRS/ HIPEC is paramount to derive the maximum oncological outcomes while minimizing the risks of postoperative complications and mortality. When expressed in Escherichia coli, the gonococcal PilD protein functions to process gonococcal prepilin in a manner consistent with its being gonococcal prepilin peptidase. The depolarization difference between linear and circular states varies significantly between samples. In contrast, general screening for phenylketonuria (PKU) remains undisputed and MS/MS screening reduced false positives by simultaneously detecting phenylalanine and tyrosine.

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The mechanisms by which Helicobacter pylori and low-dose aspirin induce gastric damage are not completely elucidated. These data are thus consistent with a constitutive secretion of beta 2m dependent upon an overexpression of MHC class I light chain as compared to the heavy chain. The lambs receiving medium- or high-dose (24 and 48 h predelivery) betamethasone had significantly lower elastance and a trend toward lower resistance when compared with the control groups. We conclude that 99mTc red blood cell scintigraphy is the preferred diagnostic technique in the investigation of suspected peripheral haemangiomas.

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Calcium-activated chloride channels contribute to the agonist-induced pulmonary artery contractions under physiological conditions, which may be a new clue to investigate the hypoxic pulmonary vasoconstriction. Intrinsic abnormalities of the myometrium, abnormal myometrial receptors for estrogen, and hormonal changes or altered responses to ischemic damage during the menstrual period may be responsible for the initiation of (epi)genetic changes found in these tumors.

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A novel swine model of subarachnoid hemorrhage-induced cerebral vasospasm. The study will describe the characteristics of patients presenting with primary lung cancer in the participating pneumology departments during the year 2010, and their diagnostic and therapeutic management, and assess changes over the last ten years. Nitrate and alanine were found to stimulate partially purified maize leaf phosphoenolpyruvate carboxylase under specific assay conditions. In 2003, an outbreak of highly pathogenic avian influenza occurred in The Netherlands.

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After 20 minutes, concentrations of 5-FU and its metabolite FdUrd were determined by HPLC in different organs and the liver tumor. This study also showed that SMSG technology is a very useful approach to rapidly define the minimal deleted region and to identify target TSGs in a given cancer. Decreased sensitization and elicitation of contact allergens in vitiliginous skin has been described. The posterior acetabular wall (PAW) is a structure easily viewed on plain radiography and its position can help guide acetabular component position.

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Mild dilated cardiomyopathy and increased left ventricular mass predict mortality: the prospective P2C2 HIV Multicenter Study. Inorganic Nitrate in Angina Study: A Randomized Double-Blind Placebo-Controlled Trial. In the experiments, DNA sequence variations were generated with error-prone PCR and were inserted in the promoter region of the cat (chloramphenicol acetyl transferase) gene on a plasmid. Inhibition of HDAC increases Runx2 acetylation, and potentiates BMP-2-stimulated osteoblast differentiation and increases bone formation. After 12 d, the patient underwent re-transplantation due to primary graft non function.

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Thyroid stimulating hormone inhibits rat granulosa cell steroidogenesis in primary culture. However, the mechanism for this effect and its consequences for cellular signaling are poorly understood. A new biochemical model for lactose transport system in this organism is presented, in which a specific membrane protein (M protein) plays the role of the sugar carrier. Metabolism of mono- and diacyl esters of tropane-3 alpha, 6 beta-diol in the Solanaceae. The role of the trustee--and his responsibility to the constituent societies in his district.

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Supercooperativity in platelet aggregation: substituted pyridyl isoxazoles, a new class of supercooperative platelet aggregation inhibitors. The recovery rates of CFU-GM and BFU-E also decreased progressively with the duration of frozen storage, to 50 and 43.5 percent, respectively, after 12 months and to 0 percent (both) after 24 months. Involvement of the small intestine first manifested as abdominal pain and later progressed to gastrointestinal bleeding with subsequent dissemination of the infection. Hence, low-dose weekly subcutaneous methotrexate may be safe and effective in inducing complete and sustained remission of this condition.

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We report here the lack of CD40L expression in four unrelated male children with the hyper-IgM syndrome. Dual phase and rate coding in hippocampal place cells: theoretical significance and relationship to entorhinal grid cells.

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Chemical and organoleptic changes in poultry meat resulting from the growth of psychrophylic spoilage bacteria at 1 degree C.56. The present parasite has been passaged through rats (SD strain) in these 8 years. Excitation-emission matrix fluorescence spectroscopy combined with parallel factor analysis (EEM-PARAFAC) and two-dimensional correlation spectroscopy (2D-COS) were applied to evaluate the effects of anthropogenic impoundment on the characteristics of dissolved organic matter (DOM) and its heavy metal binding affinity. Obviously such methods are needed to analyze data from multi-unit recordings. We report the results of our experiments on six major image classification data sets and show that the proposed approach significantly outperforms the baseline algorithms.

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The IOWA functional rating system questionnaire was performed at follow up evaluation. In the present study, we evaluated the effect of in vitro treatment with minodronate and/or docetaxel on the proliferation by cell count, the induction of apoptosis by terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) assay, and the biological activity of osteoclast by pit formation assay in human bladder cancer cell line, UMUC-14, and mouse osteoclast cells. The plain radiographs of the cervical spine, and CT scan later, confirmed the presence of C1-C2 rotatory subluxation.

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In the case of disturbed chromatin condensation the histones persist, which can be demonstrated by aniline blue staining. Hepatoprotective effects of Methyl ferulic acid on alcohol-induced liver oxidative injury in mice by inhibiting the NOX4/ROS-MAPK pathway. Reflections on mental retardation and eugenics, old and new: Mensa and the Human Genome Project.

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Changes in the nail unit in patients with secondary lymphoedema identified using clinical, dermoscopic and ultrasound examination. Intra-operative pain perception in tooth extraction--possible causes. This structural evolution is driven by the distinct interface formation energy at different CdS facets as indicated by ab initio calculation. We used Goldmann perimetry to measure the visual fields of patients who underwent vitrectomy to manage idiopathic full-thickness macular holes using either room air or humidified air for fluid-air exchange. To measure the distances between the internal mammary arteries (IMAs) and the sternum for determining a route for parasternal transthoracic interventions.

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Marker D5S416 provided the highest pairwise LOD score, and multipoint and haplotype analyses restrict the critical region to about 5.3 Mb on 5p15 between markers D5S1987 and D5S416. This study provides the viability of species in only specific environment. The same was true when the sequence of stimulations was reversed: in this case there was a decrease in amplitude of the testing response to vestibular stimulation.

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Successful Resuscitation of a Patient with Life-Threatening Metabolic Acidosis by Hemodialysis: A Case of Ethylene Glycol Intoxication. The aim of the study was to assess the in vitro and in vivo efficacy of ceftriaxone, vancomycin and rifampicin alone and combined against Streptococcus pneumoniae ATCC 51916 (MIC of ceftriaxone: 32 mg/L). The impact of international recruitment on healthcare delivery in France. Outcomes research is important because it allows us to critically evaluate our results and strive for quality improvement, share our experiences with our colleagues, and improve the care and results delivered to the patient. Adrenocorticotropin responses to naloxone in sons of alcohol-dependent men.

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Palliative treatment of neoplastic stenoses of the hepatic canal by transtumoral drainage. Rapid methods for nucleic acids extraction from Petri dish-grown mycelia.

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A stimulating electrode was positioned within the medial rectus subdivision of the oculomotor nucleus. Fabrication of water-dispersible single-walled carbon nanotube powder using N-methylmorpholine N-oxide. Gene expression in the conversion of early-phase to late-phase long-term potentiation. Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images. Further studies are needed to clarify the risk of cancers in association with cosmic radiation, other workplace exposure, host factors, and leisure sun-exposure, as clothes, and glass in cockpit windows shield pilots from the most potent ultraviolet-radiation.

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Colonization and mortality was observed within 48 hours in the group of hamsters infected with the reference toxigenic strain. We studied proline-rich divergent homeobox gene Hex/Prh expression in the dorsal skin of chick embryo during feather bud development. In this study, we utilized high-resolution structural imaging and task-state functional magnetic resonance imaging (fMRI) to assess brain structure and motor function in a homogeneous cohort of HIV-infected patients. We have cloned a developmental isoform of FTZ-F1 and found that it is expressed as a product of the previously identified, midprepupal chromosome puff at 75CD.

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Malignant enterochromaffinlike cell carcinoid of the gastric stump: an ultrastructural study. The rat mesentery was loaded with dichlorofluorescein (DCFH) diacetate, a hydroperoxide-sensitive fluorescent probe that is trapped within viable cells as a nonfluorescent form and is converted to fluorescent dichlorofluorescein (DCF) by hydroperoxides. The analysis of mixed mutant collections using microarray-based detection procedures appears to be particularly effective in identifying functions required for complex processes such as virulence. Two other MDR cell lines were investigated and low A/B ratios were found in both cases.

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Typically, individuals unaware of any underlying liver illness presented with variceal bleeding, occasionally fatal. Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells. Among phosphoinositide-specific phospholipase C, the beta(1) isoform appears to be one of the key players of the nuclear lipid signaling.

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forsythia infection and fatty food liking preceding the occurrence of fat accumulation and IR. Building with ions: towards direct write of platinum nanostructures using in situ liquid cell helium ion microscopy. Using taurine/alphaKG dioxygenase (TauD) as a paradigm for this enzyme family, time-dependent inhibition assays showed that Co(II) and Ni(II) follow slow-binding inhibition kinetics.

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Multidimensional generation of combinatorial organic arrays by selective wetting inscription. Detection of Helicobacter pylori DNA by PCR in gastrointestinal equipment. The longer survival rate of SPR seems to be independent of the rate of infectious otorrhea but depends probably on other effects of biocompatibility.

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Although a neutrophil-rich alveolitis was observed initially in both groups, the leukocytic influx and mild morphologic changes in DE-treated animals resolved within 7 days. Unanimous agreement as to the presence of an unsafe driving sequence was found in 63 (25 per cent) commercials.

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Compared with the unprotected ankle, the taped ankle had a significant increase in the proprioceptive amplification ratio. Mortality and fertility data were measured in a cohort of women recruited from the survey in 1986 and followed until 1989. Modulating Excitonic Recombination Effects through One-Step Synthesis of Perovskite Nanoparticles for Light-Emitting Diodes. This treatment was made possible by the introduction of new imaging methods such as CT which allowed better detection of the fracture pathology and provided the basis for new surgical strategies.