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Karum (Clopidogrel)
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Clopidogrel

Karum is used alone or together with aspirin to lessen the chance of a heart attack or stroke. It is given to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with other circulation problems that could cause a stroke or heart attack.

A heart attack or stroke may occur when a blood vessel is blocked by a blood clot. Karum is a platelet inhibitor. It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood. Karum may also increase the chance of serious bleeding in some people.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Pho81p only interacts with Pcl5p when Gcn4p is rapidly degraded but constitutively interacts with Pcl7p. Regional cortical thinning in preclinical Huntington disease and its relationship to cognition. Our primary aim was to determine the proportion of children discharged with abnormal vital signs and the frequency and nature of adverse events.

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Expression profiling and integrative analysis of the CESA/CSL superfamily in rice. The effects of vagus nerve stimulation on pro- and anti-inflammatory cytokines in humans: a preliminary report.

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Detection of cells producing murine interferon-alpha using antipeptide antibodies. There was a divergence in the number of sleep complaints between those with no morbidity and those who had a high degree of comorbidity. Extracutaneous mycosis fungoides of the gastrocnemius muscle mimicking sarcoma.

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Cohort study on living arrangements of older men and women and risk for basic activities of daily living disability: findings from the AGES project. Deep Uncertainties in Sea-Level Rise and Storm Surge Projections: Implications for Coastal Flood Risk Management. Qualification characteristics of specialists--graduates of medical and pharmaceutical institutes The NMDAR subunit NR3A is most highly expressed during the second postnatal week, when synaptogenesis reaches peak levels. Developing and validating an index for measuring health in patients with ankylosing spondylitis.

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Findings from this review suggest a need for research that moves conceptually and methodologically beyond a focus on the individual to a focus on the dyad and the interpersonal, institutional, and cultural sources of minority stress that affect couple relationships. An investigation into the use of the dynamic method of calibration of cardiac output. The results of the study may aid managers in applying ergonomic interventions with time and cost savings, and enhance worker satisfaction and motivation due to improvements in working conditions to prevent WMSDs. Religious service attendance only had a protective effect against suicide death among those in later (2000-2010) rather than earlier (1998 and earlier) data collection periods.

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Three screen tasks were used for determining a reference of ideal dimensions of a pen-based product. Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Physical access to tobacco is a critical public-health issue because, given that smokers have been shown to be price sensitive, lowering access costs (e.g., reduced travel time) is likely to increase consumption.

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This region is an immunodominant segment of gp41, and high levels of antibodies against this epitope have been detected in both serum and cerebrospinal fluid of HIV-infected individuals at all stages of HIV infection. An Ingenuity Pathway Analysis was conducted afterwards to identify genes and pathways epigenetically affected by GDM. These results have important implications for the processes of learning and memory storage in neocortex. High viral load, high-dose steroids, and myeloablative conditioning were associated with prolonged shedding of HCoV in HCT recipients. Neck exploration including left hemithyroidectomy and partial thymectomy failed to reveal the abnormal parathyroid gland.

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Native-English listeners were exposed to Mandarin-accented words, produced by a single talker or multiple talkers. Comorbidities in pulmonary tuberculosis cases in Puducherry and Tamil Nadu, India: Opportunities for intervention. In particular, there was no benefit of nonrigid registration techniques over the other methods evaluated in this study. The patterns of FISH signals in the two species differed greatly.

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In particular, we show that the overexpression of miR-128 - a brain enriched miRNA - causes morphological changes in SH-SY5Y neuroblastoma cells similar to those observed using an siRNA specifically directed against truncated NTRK3, as well as a significant increase in cell number. In saline a strong antibacterial effect was seen to all tested species, Gram-negative and Gram-positive, and sphingosine not selectively acted against pathogens, as health promoting bacteria were also affected. Iatrogenic Adrenal Insufficiency Secondary to Combination Therapy with Elvitegravir/Cobicistat/Tenofovir Disoproxil Fumarate/Emtricitabine and Interlaminar Triamcinolone Injection in an AIDS Patient. The aims of this study were to define the mRNA expression profiles of MYCN, DDX1, TrkA, and TrkC in biopsy tumor samples from 64 Brazilian patients with neuroblastomas of different risk stages and to correlate altered expression with prognostic values. aromaticum, as well as its main component (eugenol), possesses antiulcer activity.

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While there is now a clear consensus that American eugenics provided significant material and ideological support for the Germans, the evidence remains less clear in the British case where comparatively few figures openly supported the Nazi regime and the left-wing critique of eugenics remained particularly strong. Factors like eating disorders and gastrointestinal diseases are recognized as intrinsic factors for dental erosion. A number of opportunistic agents may cause retinitis or retinochoroiditis in patients with the acquired immunodeficiency syndrome.

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The United States Army sought to create a legally defensible, scientifically validated physical pre-employment screening test. Inheritance analysis and mapping of quantitative trait loci (QTL) controlling individual anthocyanin compounds in purple barley (Hordeum vulgare L.) grains. The presence of the TdT enzyme was assessed and specific monoclonal antibodies to the different hemopoietic lines were used to evaluate blast cells in 38 patients with blast crisis during Ph-positive CML. Microvascular resuscitation strategies include hemodynamic resuscitation using the linked combination of volume resuscitation, judicious vasopressor use, and inotropes and vasodilators.

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A series of functional studies were performed to assess the potential role of the ras-related transformation suppressor gene, Krev-1, in suppressing prostate cancer cell growth. No significant differences were observed between the two groups. Outcome was not related to age and sex, but etiology of SE significantly influenced outcome. Fourier transform infrared spectroscopy revealed strong interactions (mainly salt formation) that account for the positive deviation between measured and estimated Tg values. Stepwise changes in the model included (1) altering the endotracheal tube position to a gravity-independent position, (2) adding fluid traps, (3) humidifying air near the test lung, and (4) simplifying test lung and filters.

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The combination of site specific mutagenesis of the three ZDHHC6 palmitoylation sites, experimental determination of kinetic parameters and data-driven mathematical modelling allowed us to obtain detailed information on the eight differentially palmitoylated ZDHHC6 species. An inexpensive high intensity lamp unit for phase-contrast time-lapse cinemicrography. Plasma sphingomyelin concentration is correlated with atherosclerosis development and is an independent predictor of coronary artery disease. However, the amplitudes of evoked inhibitory postsynaptic currents, delayed inhibitory postsynaptic currents and miniature inhibitory postsynaptic currents were significantly reduced. The application of high-field magnetic resonance perfusion imaging in the diagnosis of pancreatic cancer.

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XIII: Immune response to the DNP hapten conjugated to polyacryl starch microparticles. Repeating fragments in biological sequences are often essential for structure and function. Our combined studies reveal that 2G12 is capable of binding both the D1 and D3 arms of the Man(9)GlcNAc(2) moiety, which would provide more flexibility to make the required multivalent interactions between the antibody and the gp120 oligomannose cluster than thought previously. Four themes of the workflow process emerged: pharmacist consultation, in-hospital LAI administration, discharge planning, and outpatient treatment.

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Acute management with a case report of early surgical intervention. Description of a systematic approach to the neck for removal of lymph node bearing tissues in levels I-V. The possible interaction between p53 and miRNAs in regulating gene expression was investigated using human colon cancer HCT-116 (wt-p53) and HCT-116 (null-p53) cell lines. Further research that reports cost estimates that are setting-specific across different sectors of care are required.

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The aim of this study was to quantify the effect of cardiac anisotropy in the activation-based inverse problem of electrocardiography. Chemoattractants such as the C5a peptide, derived from the C5 complement factor, bind to inhibitory guanine nucleotide binding protein (Gi)-coupled seven membrane-spanning receptors expressed in neutrophils. Inhibition was seen with a C-terminal peptide corresponding exactly to the C-terminal 11 amino acids of the processed PR14, whereas a peptide containing a sequence situated further from the C terminus was less effective. In summary, our studies indicate that serial passage of a GP64 mutant library yielded specific variants with improved HAE cell tropism, yielding tools with the potential to improve the success of gene therapy for airway diseases. Erythromycin administration attenuates cerebral damage and postoperative cognitive decline after coronary artery bypass grafting surgery.

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The regulation of metabolic genes and major virulence genes indicate that the dominant antigens might differ during the infection process and that vaccines based on these antigens might allow establishment of a precise and targeted immune response during the early phase of infection. Chloride-Templated Macrocyclization and Anion-Binding Properties of C2-Symmetric Macrocyclic Ureas from Sucrose. Depressed subjects with a family history of alcoholism have a significantly higher prevalence of reported childhood physical and sexual abuse and post-traumatic stress disorder (PTSD), make more suicide attempts, and have greater intent to die at the time of their most lethal suicide attempt, compared to depressed subjects without a family history of alcoholism. There is a relationship between the radioisotope marker molecule size and the injection-to-intra-operative evaluation time. The purpose of this study was to measure the length of the root of maxillary lateral incisors (MLI), as well as the width and depth of the concavities of their proximal surfaces, and also to determine the prevalence of palato-gingival grooves.

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Thirty-eight questionnaires filled out by clinical instructors from six four-year nursing universities and 106 questionnaires from nurse preceptors from three high-level general hospitals in the Seoul metropolitan area were analyzed to obtain quantitative data. Influence of Sodium Chloride on the Formation and Dissociation Behavior of CO2 Gas Hydrates. The usher serves as a molecular gatekeeper, allowing the ordered incorporation of the pilus subunits into the pilus structure from the periplasmic chaperone complexes. The second glycolipid fraction migrated as seven-sugar components and reacted with mAbs specific for type 1 difucosyl (ALeb) as well as Leb determinants. There is growing evidence in the neuropsychological literature that growth hormone (GH) deficiency is associated with cognitive impairment.

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Effects of two different regimens of recombinant human growth hormone therapy on the bone mineral density of patients with growth hormone deficiency. We hypothesized that addition of pentostatin to GVHD prophylaxis with tacrolimus and mini-methotrexate may improve outcomes, and we conducted a Bayesian adaptively randomized, controlled, dose-finding study, taking into account toxicity and efficacy. Chronic iron supplementation (3000 mg kg(-1) diet) for 6 weeks significantly increased plasma iron and ferritin levels.

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Potentiation of the antitumor effect of Merocyanine 540-mediated photodynamic therapy by amifostine and amphotericin B. Ultrasound biomicroscopy (UBM) confirmed the area of iridocorneal contact. Insulin regulation of GnRH gene expression through MAP kinase signaling pathways. It is concluded that a better training of these professionals will contribute to reduce the suicide impact on the community.

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Breast-feeding initiation among post-Caesarean women of the Negev, Israel. The structures of the new macrolides were determined by spectral analyses, including 2D NMR techniques. The definition of shape index (SI) and the experimental conditions under which the measurements should be conducted are given, and the relationship between SI and morphological index, which is often used to quantitatively assess red blood cell morphology, is established. F(1) hybrids of the cross were obtained following embryo rescue, and were investigated for their cytological behaviour and subjected to genomic in situ hybridization (GISH) and amplified fragment length polymorphism (AFLP) to determine the contribution of parental genomes. Paravertebral venous access for closure of a collateral in a pediatric patient after Fontan operation.

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Controlled radical fluorination of poly(meth)acrylic acids in aqueous solution. Spinal cord injury: bridging the lesion and the role of neurotrophic factors in repair.

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Substitutions at other positions, including those immediately C-terminal to M139, had no effect on steroid-binding affinity and/or specificity. Crystal structure of the C-terminal domain of S.cerevisiae eIF5. Intramolecular interactions in the triplet excited states of benzophenone-thymine dyads. This platform vastly minimizes the experimental efforts both for inorganic material interface engineering and cell biological assessments in a facile and effective approach.

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Dissemination of a Child Passenger Safety Program Through Trauma Center-Community Partnerships. Whereas activation of bitter taste receptors (T2Rs) stimulates surrounding epithelial cells to release antimicrobial peptides, activation of the sweet taste receptor (T1R) in the same cells inhibits this response. Given that foot motor cortex representation is often bilateral, we focused on the lateralization for the tibialis anterior muscle cortical motor representation and its relation to the seizure focus. Multiheme cytochromes c constitute a widespread class of proteins with essential functions in electron transfer and enzymatic catalysis.

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Odorant receptor expression has been reported in a variety of non-olfactory cells and tissues in several animal models. Chirality and neuropsychiatric drugs: an update on stereoselective disposition and clinical pharmacokinetics of bupropion. This paper examines recent research on toxic neuropathy and potential therapeutic developments. While some known approaches try to solve this problem in k-space, this study addresses it in the spatial domain and uses a modified SENSE reconstruction to reduce or completely remove ghost-type artifacts arising from processes such as motion or flow during data acquisition. Management of pain in perioperative settings remains a challenge.

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