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Losart (Losartan)

Losart is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.

Losart is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Losart relaxes the blood vessels. A lower blood pressure will increase the supply of the blood and oxygen to the heart.

Losart is also used to decrease the risk of stroke in patients with high blood pressure and enlargement of the heart. It is also used to treat kidney problems in patients with type 2 diabetes and a history of hypertension.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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As a result of these investigations, we do not recommend the use of EMLA cream in wounds. The levels of nuclear factor (NF)-kappaB proteins in nuclear extracts were analyzed by gel retardation assay.

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The statistical data processing was conducted using statistical methods such as arithmetic average, the student t-test, percentage or rate, sensitivity, specificity and accuracy of the test. This disorder is due to the genetic defect of uroporphyrinogen III cosynthase. Listeriolysin O Regulates the Expression of Optineurin, an Autophagy Adaptor That Inhibits the Growth of Listeria monocytogenes. One is the neural circuitry involved with the primary senses of smell, hearing and vision and the other is the neural circuitry of memory. This study indicates that transplantable subrenal capsule xenografts of human prostate cancer tissue in NOD-SCID mice can, as distinct from primary cancer tissue, be successfully grown in the orthotopic site.

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Therefore, TYK2 promoter variant may be also associated with the pathogenesis of T1D, modulating Th1/Th2 balance. Establishing an Ultrasound Curriculum in Undergraduate Medical Education: How Much Time Does It Take?

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Neuropathic pain is the most difficult pain to manage in the pain clinic, and sleep problems are common among patients with chronic pain including neuropathic pain. In the case of metallic tubes the lower-energy G mode is significantly broadened, however maintaining the Lorentzian line shape, in contrast to the theoretically expected asymmetric Breit-Wigner-Fano line shape from phonon-plasmon coupling.

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Venoarterial extracorporeal membrane oxygenation is a rescue therapy in patients with severe cardiopulmonary failure. In this review, different aspects of the biology of dermatophytes are addressed, with emphasis on the dermatophyte-host interaction and the mechanisms of antifungal resistance.

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The SOFA score by itself is an inadequate prognostic tool in patients at low risk of organ damage. Sensitive Photoacoustic IR Spectroscopy for the Characterization of Amino/Azido Mixed-Linker Metal-Organic Frameworks. Both children had a latent period prior to the onset of neurologic symptoms.

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In contrast, ectopic 60A expression had no detectable effects on embryonic development but led to defects in adult structures or lethality during metamorphosis. The main themes were oestrogen receptor alpha signalling, new techniques for mammary cell culture, CRISPR screening and proteogenomics. The methodological quality of the selected RCTs was evaluated by the Modified Jadad Score.

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In cultured human proximal tubule cells, induction of ischemia by partial adenosine triphosphate (ATP) depletion resulted in a rapid up-regulation of both Zf9 and of TGF-beta1 proteins. An increase in the number of patients with bilirrubin encephalopathy has been observed over the last few years, and we attempt to find out the causes. In a patient with fibrous dysplasia, the symmetrized body surface image was useful for confirming improvement of the real body surface.

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Episode Payment Model for Coronary Artery Bypass Grafting-Opportunities and Challenges. Survival and engraftment of mouse embryonic stem cells in the mammary gland. The course of MCC is often aggressive, with early metastasis, widespread disease, and death. Licence to Practise and Liberty to Teach Medicine in the English Provinces. These results suggest that the PAs and MMP-9 proteolytic cascade may be associated with blood-CNS barrier disruption in eosinophilic meningitis caused by Angiostrongylus cantonensis.

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An example is the expression of an extracellular protease by the lactic acid bacterium Lactococcus lactis, which degrades milk proteins into free utilizable peptides that are essential to allow growth to high cell densities in milk. Based on histological appearance, it is often described as an osteochondroma or osteochondroma-like lesion, although clinical differences exist between DEH and osteochondromas. However, positive outcomes of social support might be more dependent on the way support is provided than the amount of support received.

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DNA of blood samples from all affected individuals, suspected individuals and unaffected relatives of the family was extracted and amplified to detect the polymorphisms at loci D22S1150 and D22S268 that are linked with the NF2 gene. Data from 502 women and 425 men from the population-based Study of Health in Pomerania (SHIP-TREND) were used. Volume of distribution and clearance of peptide-based nanofiber after convection-enhanced delivery. Although some of the circumstances encountered by Latino parents resemble those typically found in the literature about ADHD and families, their experience is rendered inordinately complex by multiple overlapping sociocultural, linguistic, and parental circumstances.

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AIHW data from 2005/2006 to 2012/2013 was used to assess changes in surgical mortality. Fracture with non-union through an incomplete preaxial distal symphalangism. The data indicate that our protocol is highly sensitive for recording choice behaviour in acridids and reveals the potential they have for advancing our current understanding of associative learning and the field of learning in general. The two study groups were similar in terms of long-term nutritional exposure, sociodemographic, socioeconomic, clinical, and biological features.

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Three distinct nuclear protein binding sites in the promoter of the murine multidrug resistance mdr1b gene. During the onset of mitosis, we observed that a fraction of B23 associates with, and dissociates from, the poles later than NuMA. Traumatic hip dislocations can have devastating complications such as osteoarthritis or osteonecrosis. Stimulating receptor-expressing Sf9 cells with a mixture of numerous odorous compounds elicited a significant and dose-dependent second messenger response, which was never observed in control cells.

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A rare case of adenocarcinoma arising within a duplication cyst of the rectum: curative excision with 9-year follow-up. oshimensis varied from 1262 to 47,235 mg kg(-1), but the DTPA-extractable As concentrations were relatively low, with a maximum of 65 mg kg(-1). Dynamic expression patterns of imprinted genes in human embryonic stem cells following prolonged passaging and differentiation. Pregnancies and offspring in survivors of acute lymphoid leukemia and lymphoma.

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Nevertheless, this study has limitations in that it did not evaluate the impact of the socioeconomic and psychological factors that are important contributors to this type of poisoning. Increased number of macrophages in both groups may result in a decreased level of some inflammatory mediators. Incident-photon energy-distribution effects on radiationless resonant Raman scattering. First, the proposed method seeks to improve pose estimation accuracy by adding the depth channel to DPM, which was formerly defined based only on red-green-blue (RGB) channels, in order to obtain a four-dimensional DPM (4D-DPM).

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A report to the Intermational Commission on Radiation Units and Measurements. To find a common TCR regulatory element, we have studied the ability of the newly described enhancer-binding protein Gata3 to bind to the sequence motif (A/T)GATA(G/A) shared between enhancer elements of all four TCR genes. Recombinant erythropoietin (EPO) is used to correct for anaemia caused by chronic renal failure or cancer therapy. Mediators and moderators of magazine advertisement effects on adolescent cigarette smoking. A multiple linear regression model was used to determine the factors associated with the EQ-5D index and EQ-VAS score among study participants.

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The authors compare the results obtained by CT with clinics and conventional radiography in the staging of nasopharyngeal tumors. BA, apart from its cytotoxic activities in cellular systems, is capable of inducing differentiation of NHK into corneocytes without immediately provoking apoptotic cell death. The automated assessment method we used could enhance behavioral teratology studies of avian species. Number and affinity of transferrin-receptors at the placental microvillous plasma membrane of the guinea pig: influence of gestational age and degree of transferrin glycan chain complexity. national surveys in prostate cancer conducted by the Patterns of Care Study in radiation oncology and the prostate cancer database from the Department of Radiation Oncology of the Fox Chase Cancer Center (Philadelphia, PA) have been used to compare processes and outcomes of conventional radiation treatment with conformal three-dimensional (3D) radiation treatment in elderly patients (older than or equal to 70 years) compared with younger patients.

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Preliminary experiences with limbal relaxing incision for treatment of astigmatism during phacoemulslfication. Evolutionary theory predicts that the rate and level of adaptation will be enhanced in sexual relative to asexual genomes because sexual recombination facilitates the elimination of deleterious mutations and the fixation of beneficial ones by natural selection.

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Lastly, we find mixed evidence for a relationship between the level of sexual dimorphism in attraction traits and the between-sex correlation in gender dimorphic plants. There was a correlation between the concentration of noxious substances as part of the ambient air and the prevalence of allergic diseases in children. To gain better insights into the involvement of these two transcription factors in the onset of the innate immune response and to identify their regulatory network in activated macrophages, DNA microarray was employed. Moreover, administration of ALGERNON to pregnant dams rescued aberrant cortical formation in DS mouse embryos and prevented the development of abnormal behaviors in DS offspring.

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After image capture, all suspicious or equivocal lesions were biopsied and examined histopathologically. It was observed that rabbit IgG to complement component C3 and albumin and mouse IgG to C5, but also heat-aggregated non-immune rabbit IgG, enhanced the agglutinating antibody response to sheep erythrocytes (SRBC). Hepatitis A virus transmission by blood products in the United States. Most of the revisions could be directly linked to perioperative surgical errors.

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Recent microbiome genome-wide association studies reveal that variants in many human genes involved in immunity and gut architecture are associated with an altered composition of the gut microbiome. Monitoring of perfusion is a cornerstone in surgery, phlebology and basic science to proof wound healing by interventions. Similarly, stimulation of untransfected L929 cells with TGF-beta1 results in suppression of IkappaB-alpha expression and retarded IkappaB-alpha degradation in response to TNF-alpha. A downmodulation of IFNgamma production was observed with the mAbs B-B46 (80228) and B-E43 (80232).

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The resulting down-regulation of PIN-FORMED (PIN) auxin efflux carriers is considered the key event in promoting differentiation of meristematic cells. Mutagenicity assays of leachate from domestic waste landfills in Japan: the establishment of a protocol for measuring mutagenicity levels of leachate. Electrophysiological effects of putative autoreceptor-selective dopamine agonists on A10 dopamine neurons. Leptin resistance contributes to the pathogenesis of common obesity related metabolic diseases, including insulin resistance.

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The increasing of In deposition rate results in the decreasing of outer and inner diameters of InP ringlike quantum-dot molecules and height of InP quantum dots but increases the InP quantum dot and ringlike quantum-dot molecule densities. The impact of repeated organophosphorus pesticide exposure on biomarkers and neurobehavioral outcomes among adolescent pesticide applicators. 6-Hydroxydopamine (6-OHDA) is an oxidative neurotoxin used to injure catecholaminergic cells of the central and peripheral nervous systems. In addition, we detected four regions with copy number changes that were frequently identified in our group of patients and therefore most likely represent genomic polymorphisms.

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Human serum cholesterol synthesis measured by deuterium labeling. The present method is used to determine the inhibitory activity of test compounds on HDAC1 and HDAC6 in cells. A major component of a clinical governance framework requires utilizing audit procedures, which assess the effectiveness of current systems and ultimately direct continual quality improvement. Finally, we demonstrate that the cytokine secretion kinetics and bacterial killing are altered in Nod1-deficient cells infected with P. to investigate whether the pulmonary activity in 201Tl myocardial scintigraphy can be accurately quantified from the anterior SPECT projection, 2.

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An association between attitude and self-efficacy and physical activity was absent. A further range of compounds is being evaluated for clinical use as HDAC inhibitors, including hydroxamic acids such as Trichostatin A (TSA) and Suberoyl anilide bishydroxamide (SAHA).

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This technique may have significant limitations when left oblique anterior views are acquired, due in part to attenuation resulting from intragastric redistribution. Six hundred and twelve consecutive sexually active IDUs over 18 years able to answer the questionnaire.

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Although Cladonia subcervicornis frequently produces apothecia, we conclude that dispersal by ascospores over long distances is rather ineffective in this species. Each band position locates nearly at the average of the corresponding vibrations in the electronic ground and excited states of the Bz monomer. We present a case of forearm compartment syndrome in a patient with mild hemophilia B who sustained an olecranon fracture.

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We found that monooxidized ubiquitins were more susceptible to further oxidations by subsequent laser irradiation, as compared to nonoxidized ones. Comparative clinical trial of standard operative tracheostomy with percutaneous tracheostomy. Families of children with severe TBI and low resources reporting deteriorating functioning over the follow-up interval. CCA cells transfected with shNEAT1 also exhibited reduced metastasis and invasiveness in Transwell assays. Benign bone tumours are pathologies frequently encountered in archaeological human remains, with the most common being osteoma and osteochondroma.

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In both apes, forelimb posture was correlated with substrate size during both ascent and descent climbing. The reasons for diagnosis were because the abnormal shadow appeared after the inhalation of volcanic ash, chest computed tomography showed diffuse irregular shadows with air bronchogram, thoracoscopic lung biopsy showed cellular-bronchiolitis around crystals, and the results of mineralogical analysis of the particles in alveolar macrophages detected in the biopsy specimen by scanning electron microscopy (SEM) were very similar to those of volcanic ash. These proteins, which have host defense and antibacterial activities, may play a significant role in the early response to invasion of mammary tissues by pathogenic bacteria.

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Blocking layer A strongly attenuated the visual responsiveness of about half of the cells tested. Does internet-based cognitive behaviour therapy reduce healthcare costs and resource use in treatment of social anxiety disorder? The relation between endometriomas and damage to ovarian reserve remains controversial. Whereas the HR response showed the expected tri-phasic profile there were no significant between valence differences.

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Villous composition and membrane thickness in the human placenta at term: a stereological study using unbiased estimators and optimal fixation techniques. We hypothesized that the incidence of POCD would be related to changes in cortisol level. All Ultrasound Doppler studies were performed by the same radiologist. Twenty-two patients with pilomatricoma seen from January 1986 to October 1990 were analyzed retrospectively.

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Nonetheless, these models do not completely replicate in vivo proteolysis or the complex biogeography of the gastrointestinal tract. In the present studies, we examined the effects of acute exposure of rats to the pulmonary irritant, ozone (O3), on production of these mediators by lung phagocytes. A large linear dynamic range is mandatory if both low- and high-abundance ions have to be detected and quantitated in heavy matrix samples. Nonetheless, many Chinese people are still not familiar with the principle, testing types, technologies used in this process, application and benefits to society, and national or international administration of genetic testing. Self-Awareness for Memory Impairment in Amnestic Mild Cognitive Impairment: A Longitudinal Study.

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Serum C-reactive protein (CRP) increases and albumin decreases in patients with inflammation and infection. With this recognition comes the need for researchers to implement proper trial design and for the clinician to be able to interpret results as they apply to clinical practice. The two higher doses, 420 and 840 mg, gave a significant increase in the frequency of X-Y univalents and breaks over those of the vehicle control. The problem of boredom in people with cancer has received little research attention, and yet clinical experience suggests that it has the potential to profoundly affect quality of life in those patients. Characterization of patients with suspected hypersensitivity to cervicovaginal fluid.

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Experimental study on application of antineoplastic drugs using autoradiography The purpose of this study was to investigate the effect of 17beta-estradiol (E(2)) on the proliferation of fibroblasts derived from cardinal ligaments in women with or without POP. Identification by site-directed mutagenesis of amino acid residues in ribosomal protein L2 that are essential for binding to 23S ribosomal RNA. Lavandula officinalis and venlafaxine, herbal and chemical drugs respectively, are used to treat depression.

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Ixodes scapularis ticks play an important role in the transmission of a wide variety of pathogens between various mammalian species, including humans. On admission, we initiated intravenous ampicillin-sulbactam and aztreonam.

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This may be due to persistent inflammation in peri-implantitis tissues after initial mechanical bisogamma 5 bisoprolol dosage treatment. Surgical treatment consists in debridement, arthroscopic capsular release, and removal of bone fragments by arthroscopy. Growth and the nutritional status of nonsteroid-dependent asthmatic children. Reactions to it are, however, socially constructed and patterned. Isolation and partial characterization of antibody- and globin-enriched complexes from membranes of dense human erythrocytes.

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Interestingly, host NK cells did not modify the outcome of unconditioned HSCT as long as the early B-cell compartment was compromised. A 62-year-old woman with a history of liver problem and proximal muscle weakness was admitted with atraumatic fracture of the left distal humerus due to osteomalacia. Here, we report 1 novel duplication mutation of the FOXL2 gene identified in a large Chinese family affected by type II BPES and 1 less recurrent 17-bp duplication in a large Chinese family affected by BPES of an undetermined type. Initial neonatal retinal vascularization assays showed their respective bioactivities in vivo. Solenoidal microcoils have greatly enhanced the mass medoclav forte las vegas limits of detection of NMR, enabling the on-line coupling of microseparation and concentration techniques such as capillary isotachophoresis (cITP), which can separate and concentrate analytes by 2-3 orders of magnitude.

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To correlate the cytologic grade of breast carcinoma with the expression of E-cadherin/catenin system molecules and the presence of metastasis in regional fosinopril side effects erectile lymph nodes. Clear, focused, and evidence-based treatment algorithms are needed to support primary care physicians, neurologists, and gynecologists in the treatment of this common condition.

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In the present paper we show that formation of calcareous corpuscles in cysticerci of Taenia solium is not of intracellular origin, as described for other cestodes, but occurs extracellularly in the lumen of protonephridial ducts in a way similar to that proposed for trematodes. These results suggest that dynorphin A-(1-13) prevents memory dysfunctions in ischemic mice through the activation of kappa-opioid receptors. Hypertension is a major cause of global morbidity and mortality, with high prevalence rates in Africa including Kenya. In this study, we evaluated the performance of a novel assay called ADx-SuperARMS in arthrotec 50 mg-200 mcg tab detecting EGFR mutations in plasma cell-free DNA from patients with advanced lung adenocarcinoma. However, opposite changes in labeling intensity were observed between acinar and intercalated duct granules.

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Early estrogen replacement therapy reverses the omeprazole 20 mg treatment rapid loss of trabecular bone volume and prevents further deterioration of connectivity in the rat. Lack of limb parts appears to be of secondary importance, especially in the upper limb.

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Lack of response to nivolumab in a patient norfloxacin and tinidazole with beta cyclodextrin tablets with EGFR-mutant non-small cell lung cancer adenocarcinoma sub-type transformed to small cell lung cancer. The clear sightedness of those who developed this technique is proved by its rapid acceptance and integration in basic research, prognostic factors oncology and drugs discovery, reflected in hundreds of publications.

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Segmental live celcox drug information donor pancreas transplantation: review and critique of rationale, outcomes, and current recommendations. Data on blood pressure and major cardiovascular disease (CVD) risk factors were collected from all participants.

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Construction of a plasmid vector of fused protein genes driven by human insulin-like growth factor II P3 promoter The goals of this study were 1) to determine whether the use of the Pediatric Symptom Checklist in an adult-oriented psychiatric practice was feasible, 2) to determine if scores indicative of dysfunction on the Pediatric Symptom Checklist were associated with parental or background factors, 3) to determine whether children flagged by their scores on the Pediatric Symptom Checklist were receiving psychiatric services, and 4) to compare the psychosocial dysfunction in this group of children with that found in children screened as part of routine pediatric visits. Robotic-assisted thoracoscopic surgery: state of the art and future perspectives. Two procedures are described for separating T5 replicating DNA from DNA of intracellular phage particles. Lowering cecal bacterial omeprazole drug use concentrations can diminish inflammation in remote organs.